| SP | Richard, J.Richard, J.R. >> | 30 | 1980 | R | 90 | 10 | 10 | 5 | 4 | 3.84 | .304 | 1.31 | 7.8 | 4.2 | 9.8 | 58.2 | 50 | 28 | 25 | 5 | 27 | 63 | 0 | 0 | 0 | 0 | 6 | 0 | 0 | 3.34 |
| SP | Johnson, R.Johnson, Randy # >> | 41 | 2004 | L | 84 | 9 | 9 | 4 | 4 | 4.88 | .346 | 1.55 | 9.9 | 4.2 | 7.6 | 51.2 | 56 | 29 | 28 | 6 | 24 | 43 | 0 | 0 | 0 | 0 | 5 | 2 | 2 | 4.37 |
| SP | Waddell, R.Waddell, Rube >> | 29 | 1905 | L | 67 | 9 | 9 | 3 | 3 | 5.67 | .355 | 1.61 | 11.0 | 3.5 | 6.8 | 54.0 | 66 | 34 | 34 | 6 | 21 | 41 | 0 | 0 | 0 | 0 | 2 | 2 | 1 | 4.20 |
| RP | Soriano, R.Soriano, Rafael >> | 24 | 2003 | R | 84 | 27 | 0 | 3 | 0 | 1.78 | .221 | 0.82 | 4.4 | 3.1 | 7.5 | 35.1 | 17 | 7 | 7 | 2 | 12 | 29 | 0 | 4 | 0 | 0 | 0 | 1 | 0 | 3.20 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 75 | 26 | 0 | 0 | 2 | 4.66 | .298 | 1.28 | 5.9 | 5.6 | 10.6 | 29.0 | 19 | 15 | 15 | 4 | 18 | 34 | 0 | 4 | 1 | 0 | 0 | 0 | 3 | 4.31 |
| RP | Messersmith, A.Messersmith, Andy >> | 23 | 1968 | R | 57 | 22 | 0 | 0 | 1 | 5.90 | .351 | 1.59 | 8.7 | 5.6 | 7.1 | 29.0 | 28 | 19 | 19 | 4 | 18 | 23 | 0 | 4 | 1 | 0 | 0 | 1 | 1 | 5.17 |
| RP | Marmol, C.Marmol, Carlos >> | 26 | 2008 | R | 71 | 11 | 0 | 1 | 1 | 6.17 | .386 | 1.80 | 9.0 | 8.2 | 9.8 | 11.2 | 11 | 11 | 8 | 3 | 10 | 12 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 7.36 |
| RP | Marte, D.Marte, Damaso >> | 28 | 2003 | L | 37 | 10 | 0 | 1 | 1 | 1.54 | .271 | 1.11 | 4.1 | 6.5 | 7.4 | 11.2 | 5 | 2 | 2 | 0 | 8 | 9 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 3.55 |