| SP | deGrom, J.deGrom, Jacob >> | 33 | 2021 | R | 100 | 11 | 11 | 3 | 2 | 3.58 | .301 | 1.25 | 8.7 | 2.6 | 8.4 | 70.1 | 68 | 31 | 28 | 9 | 20 | 65 | 1 | 0 | 0 | 0 | 8 | 3 | 0 | 3.80 |
| SP | Koufax, S.Koufax, Sandy # >> | 30 | 1965 | L | 97 | 11 | 11 | 4 | 6 | 4.35 | .306 | 1.32 | 9.6 | 2.4 | 8.8 | 78.2 | 83 | 39 | 38 | 11 | 21 | 76 | 4 | 0 | 0 | 0 | 7 | 0 | 2 | 3.69 |
| SP | Santana, J.Santana, Johan >> | 25 | 2004 | L | 86 | 11 | 11 | 4 | 4 | 4.21 | .273 | 1.11 | 6.9 | 3.2 | 5.7 | 68.1 | 52 | 33 | 32 | 11 | 24 | 43 | 0 | 0 | 0 | 0 | 6 | 1 | 0 | 4.94 |
| RP | Uehara, K.Uehara, Koji >> | 38 | 2013 | R | 100 | 27 | 0 | 0 | 1 | 4.05 | .275 | 1.11 | 6.8 | 3.3 | 10.1 | 33.1 | 25 | 15 | 15 | 4 | 12 | 37 | 0 | 2 | 0 | 0 | 0 | 1 | 1 | 3.52 |
| RP | Soriano, R.Soriano, Rafael >> | 24 | 2003 | R | 85 | 26 | 0 | 1 | 1 | 7.24 | .339 | 1.54 | 11.0 | 3.0 | 11.3 | 27.1 | 33 | 22 | 22 | 10 | 9 | 34 | 0 | 3 | 1 | 0 | 0 | 0 | 0 | 6.30 |
| RP | Boxberger, B.Boxberger, Brad >> | 26 | 2014 | R | 83 | 15 | 0 | 2 | 0 | 3.38 | .300 | 1.29 | 6.5 | 5.5 | 10.5 | 18.2 | 13 | 8 | 7 | 1 | 11 | 21 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 3.22 |
| RP | Holland, G.Holland, Greg >> | 27 | 2013 | R | 72 | 20 | 0 | 1 | 3 | 4.43 | .365 | 1.62 | 9.0 | 5.9 | 8.6 | 20.1 | 20 | 10 | 10 | 0 | 13 | 19 | 0 | 1 | 3 | 0 | 0 | 2 | 1 | 3.35 |
| RP | Bailey, A.Bailey, Andrew >> | 25 | 2009 | R | 67 | 16 | 0 | 1 | 2 | 3.65 | .403 | 2.03 | 12.8 | 6.0 | 8.3 | 12.1 | 17 | 5 | 5 | 1 | 8 | 11 | 0 | 2 | 1 | 0 | 0 | 0 | 1 | 4.25 |
| SP | Hudson, D.Hudson, Daniel >> | 23 | 2010 | R | 60 | 3 | 0 | 1 | 0 | 5.06 | .360 | 1.69 | 14.4 | 1.8 | 7.2 | 5.1 | 8 | 3 | 3 | 2 | 1 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 7.20 |