| SP | Kershaw, C.Kershaw, Clayton >> | 28 | 2016 | L | 99 | 33 | 33 | 12 | 18 | 3.83 | .281 | 1.16 | 8.9 | 1.6 | 8.2 | 247.0 | 244 | 111 | 105 | 24 | 43 | 224 | 10 | 0 | 0 | 2 | 20 | 3 | 2 | 3.01 |
| SP | Santana, J.Santana, Johan # >> | 25 | 2004 | L | 85 | 32 | 32 | 14 | 13 | 4.25 | .303 | 1.28 | 8.3 | 3.2 | 7.8 | 218.0 | 200 | 108 | 103 | 28 | 78 | 188 | 2 | 0 | 0 | 2 | 14 | 6 | 13 | 4.10 |
| SP | Seaver, T.Seaver, Tom # >> | 27 | 1971 | R | 71 | 32 | 32 | 15 | 10 | 5.16 | .322 | 1.40 | 10.1 | 2.6 | 7.9 | 214.1 | 239 | 124 | 123 | 23 | 61 | 187 | 13 | 0 | 0 | 1 | 13 | 6 | 3 | 3.59 |
| RP | Doolittle, S.Doolittle, Sean >> | 31 | 2018 | L | 99 | 79 | 0 | 4 | 0 | 2.76 | .274 | 1.10 | 8.0 | 1.9 | 9.5 | 98.0 | 87 | 35 | 30 | 10 | 21 | 103 | 0 | 13 | 2 | 0 | 0 | 3 | 1 | 2.96 |
| RP | Benitez, A.Benitez, Armando >> | 32 | 2004 | R | 82 | 59 | 0 | 4 | 2 | 2.90 | .291 | 1.22 | 6.7 | 4.3 | 7.1 | 71.1 | 53 | 25 | 23 | 5 | 34 | 56 | 0 | 8 | 2 | 0 | 0 | 1 | 0 | 3.82 |
| RP | Dotel, O.Dotel, Octavio >> | 29 | 2002 | R | 68 | 33 | 0 | 3 | 2 | 4.98 | .340 | 1.52 | 10.0 | 3.8 | 9.2 | 43.1 | 48 | 24 | 24 | 4 | 18 | 44 | 0 | 2 | 1 | 0 | 0 | 1 | 0 | 3.49 |
| RP | Drabowsky, M.Drabowsky, Moe >> | 31 | 1966 | R | 54 | 29 | 0 | 4 | 1 | 2.73 | .316 | 1.39 | 5.9 | 6.8 | 8.0 | 52.2 | 34 | 17 | 16 | 5 | 39 | 46 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.73 |