| SP | Martinez, P.Martinez, Pedro † >> | 29 | 2000 | R | 100 | 33 | 33 | 18 | 11 | 3.45 | .287 | 1.17 | 8.1 | 2.4 | 8.3 | 253.0 | 229 | 101 | 97 | 27 | 68 | 233 | 10 | 0 | 0 | 2 | 21 | 8 | 3 | 3.45 |
| SP | Krause, H.Krause, Harry # >> | 21 | 1909 | L | 72 | 32 | 32 | 11 | 13 | 4.39 | .299 | 1.26 | 8.4 | 3.0 | 4.8 | 207.0 | 193 | 106 | 101 | 21 | 68 | 110 | 2 | 0 | 0 | 2 | 14 | 4 | 3 | 4.30 |
| SP | Waddell, R.Waddell, Rube >> | 29 | 1905 | L | 67 | 30 | 30 | 11 | 10 | 4.88 | .337 | 1.50 | 9.2 | 4.4 | 5.6 | 202.2 | 207 | 115 | 110 | 28 | 98 | 126 | 4 | 0 | 0 | 2 | 16 | 4 | 6 | 5.07 |
| RP | Adams, M.Adams, Mike † >> | 31 | 2009 | R | 99 | 80 | 0 | 7 | 7 | 2.97 | .275 | 1.09 | 6.0 | 3.8 | 7.3 | 115.0 | 77 | 38 | 38 | 7 | 48 | 93 | 0 | 6 | 3 | 0 | 0 | 6 | 2 | 3.58 |
| RP | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 85 | 84 | 0 | 8 | 5 | 2.13 | .242 | 0.93 | 6.9 | 1.5 | 10.1 | 101.1 | 77 | 26 | 24 | 8 | 17 | 113 | 0 | 16 | 2 | 0 | 0 | 3 | 1 | 2.39 |
| RP | Marmol, C.Marmol, Carlos >> | 26 | 2008 | R | 71 | 57 | 0 | 2 | 3 | 3.03 | .305 | 1.28 | 5.6 | 5.9 | 8.8 | 59.1 | 37 | 22 | 20 | 6 | 39 | 58 | 0 | 6 | 1 | 0 | 0 | 2 | 3 | 4.44 |
| RP | Rhodes, A.Rhodes, Arthur >> | 32 | 2001 | L | 64 | 43 | 0 | 3 | 1 | 3.21 | .255 | 1.01 | 6.9 | 2.3 | 9.4 | 47.2 | 36 | 17 | 17 | 9 | 12 | 49 | 0 | 6 | 1 | 0 | 0 | 1 | 3 | 4.23 |
| RP | Russell, J.Russell, Jeff >> | 28 | 1989 | R | 57 | 31 | 0 | 1 | 3 | 3.58 | .324 | 1.41 | 7.3 | 5.6 | 6.8 | 32.2 | 26 | 13 | 13 | 2 | 20 | 24 | 0 | 3 | 0 | 0 | 0 | 1 | 0 | 4.28 |
| SP | Camnitz, H.Camnitz, Howie >> | 28 | 1909 | R | 58 | 1 | 1 | 0 | 0 | 0.00 | .313 | 1.36 | 11.6 | 1.3 | 5.1 | 7.1 | 9 | 0 | 0 | 0 | 1 | 4 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 2.29 |
| SP | Chesbro, J.Chesbro, Jack >> | 30 | 1904 | R | 65 | 6 | 0 | 0 | 2 | 3.68 | .389 | 1.91 | 11.6 | 6.4 | 3.9 | 7.1 | 9 | 3 | 3 | 1 | 5 | 3 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 6.14 |