| SP | Mathewson, C.Mathewson, Christy >> | 29 | 1909 | R | 86 | 32 | 32 | 14 | 10 | 3.34 | .269 | 1.08 | 7.9 | 1.8 | 4.2 | 229.1 | 202 | 88 | 85 | 21 | 45 | 108 | 2 | 0 | 0 | 1 | 21 | 6 | 2 | 3.92 |
| SP | Maddux, G.Maddux, Greg # >> | 29 | 1995 | R | 89 | 33 | 33 | 7 | 16 | 3.91 | .280 | 1.13 | 8.1 | 2.1 | 5.0 | 216.1 | 195 | 102 | 94 | 18 | 50 | 120 | 3 | 0 | 0 | 1 | 18 | 7 | 4 | 3.76 |
| SP | Fernandez, J.Fernandez, Jose # >> | 21 | 2013 | R | 76 | 32 | 32 | 13 | 8 | 4.27 | .311 | 1.32 | 8.1 | 3.8 | 7.5 | 183.1 | 164 | 89 | 87 | 26 | 78 | 152 | 1 | 0 | 0 | 1 | 19 | 6 | 0 | 4.56 |
| SP | Johnson, R.Johnson, Randy † # >> | 41 | 2004 | L | 83 | 31 | 30 | 18 | 7 | 3.95 | .300 | 1.26 | 8.2 | 3.1 | 8.0 | 189.1 | 173 | 87 | 83 | 12 | 65 | 167 | 2 | 0 | 0 | 0 | 15 | 5 | 3 | 3.17 |
| RP | Chapman, A.Chapman, Aroldis >> | 26 | 2014 | L | 94 | 91 | 0 | 6 | 4 | 2.35 | .276 | 1.13 | 5.4 | 4.8 | 9.4 | 118.2 | 71 | 33 | 31 | 8 | 63 | 123 | 0 | 13 | 3 | 0 | 0 | 2 | 9 | 3.45 |
| RP | Miller, A.Miller, Andrew † >> | 29 | 2014 | L | 88 | 81 | 0 | 7 | 5 | 2.48 | .230 | 0.87 | 4.9 | 2.9 | 8.3 | 98.0 | 53 | 27 | 27 | 10 | 32 | 90 | 0 | 19 | 5 | 0 | 0 | 3 | 6 | 3.56 |
| RP | Treinen, B.Treinen, Blake >> | 30 | 2018 | R | 80 | 26 | 0 | 2 | 0 | 2.06 | .234 | 0.86 | 4.4 | 3.3 | 7.2 | 35.0 | 17 | 8 | 8 | 1 | 13 | 28 | 0 | 4 | 1 | 0 | 0 | 2 | 3 | 3.06 |
| RP | Eichhorn, M.Eichhorn, Mark >> | 26 | 1986 | R | 49 | 28 | 0 | 4 | 2 | 2.78 | .264 | 1.08 | 6.7 | 3.0 | 7.7 | 74.1 | 55 | 23 | 23 | 7 | 25 | 63 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 3.54 |