| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 95 | 30 | 30 | 12 | 12 | 3.18 | .285 | 1.17 | 7.2 | 3.4 | 8.3 | 206.2 | 164 | 76 | 73 | 15 | 78 | 191 | 3 | 0 | 0 | 2 | 20 | 5 | 5 | 3.30 |
| SP | Reulbach, E.Reulbach, Ed >> | 24 | 1906 | R | 60 | 29 | 29 | 9 | 11 | 3.62 | .306 | 1.29 | 6.9 | 4.7 | 4.5 | 201.1 | 155 | 88 | 81 | 17 | 105 | 100 | 4 | 0 | 0 | 1 | 21 | 6 | 1 | 4.76 |
| SP | Overall, O.Overall, Orval >> | 28 | 1909 | R | 55 | 29 | 29 | 8 | 12 | 5.15 | .329 | 1.45 | 9.5 | 3.5 | 5.0 | 185.1 | 196 | 112 | 106 | 26 | 72 | 103 | 2 | 0 | 0 | 0 | 11 | 4 | 5 | 4.95 |
| SP | Millwood, K.Millwood, Kevin >> | 25 | 1999 | R | 52 | 29 | 29 | 8 | 15 | 5.29 | .325 | 1.43 | 9.8 | 3.1 | 5.5 | 183.2 | 200 | 109 | 108 | 28 | 63 | 111 | 2 | 0 | 0 | 1 | 15 | 2 | 2 | 4.84 |
| RP | Benoit, J.Benoit, Joaquin # >> | 33 | 2010 | R | 95 | 78 | 0 | 5 | 3 | 4.50 | .303 | 1.29 | 7.9 | 3.7 | 7.4 | 108.0 | 95 | 55 | 54 | 21 | 44 | 89 | 0 | 2 | 5 | 0 | 0 | 2 | 4 | 5.16 |
| RP | Gossage, R.Gossage, Rich † >> | 30 | 1981 | R | 90 | 67 | 0 | 8 | 5 | 4.09 | .302 | 1.23 | 7.1 | 4.0 | 8.8 | 77.0 | 61 | 35 | 35 | 11 | 34 | 75 | 0 | 8 | 2 | 0 | 0 | 5 | 3 | 4.43 |
| RP | Dotel, O.Dotel, Octavio >> | 29 | 2002 | R | 69 | 51 | 0 | 2 | 5 | 3.26 | .266 | 1.07 | 5.9 | 3.7 | 9.3 | 58.0 | 38 | 23 | 21 | 5 | 24 | 60 | 0 | 7 | 1 | 0 | 0 | 1 | 1 | 3.34 |
| RP | Abernathy, T.Abernathy, Ted >> | 34 | 1967 | R | 49 | 17 | 0 | 1 | 1 | 2.53 | .273 | 1.13 | 7.3 | 3.0 | 3.9 | 21.1 | 17 | 6 | 6 | 4 | 7 | 9 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | 5.62 |
| RP | Rodriguez, F.Rodriguez, Felix >> | 29 | 2001 | R | 42 | 20 | 0 | 1 | 0 | 1.75 | .238 | 0.90 | 5.4 | 2.9 | 6.8 | 25.2 | 15 | 5 | 5 | 0 | 8 | 19 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 2.56 |
| SP | McQuillan, G.McQuillan, George >> | 23 | 1908 | R | 48 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Vaughn, H.Vaughn, Hippo >> | 30 | 1918 | L | 41 | 4 | 0 | 1 | 1 | 1.86 | .194 | 0.72 | 6.0 | 1.0 | 3.0 | 9.2 | 6 | 4 | 2 | 0 | 1 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2.67 |