| SP | deGrom, J.deGrom, Jacob >> | 33 | 2021 | R | 100 | 27 | 27 | 11 | 8 | 3.44 | .280 | 1.15 | 7.8 | 2.6 | 9.7 | 196.0 | 170 | 75 | 75 | 24 | 56 | 211 | 4 | 0 | 0 | 1 | 19 | 3 | 0 | 3.34 |
| SP | Kluber, C.Kluber, Corey # >> | 31 | 2017 | R | 89 | 26 | 26 | 9 | 11 | 4.45 | .314 | 1.35 | 9.1 | 3.0 | 8.6 | 186.0 | 188 | 97 | 92 | 19 | 63 | 178 | 3 | 0 | 0 | 0 | 10 | 4 | 5 | 3.49 |
| SP | Johnson, R.Johnson, Randy # >> | 41 | 2004 | L | 84 | 26 | 26 | 10 | 13 | 5.59 | .323 | 1.40 | 9.6 | 3.1 | 8.0 | 180.1 | 192 | 113 | 112 | 25 | 61 | 160 | 4 | 0 | 0 | 1 | 10 | 5 | 3 | 4.13 |
| SP | Cicotte, E.Cicotte, Eddie # >> | 33 | 1917 | R | 74 | 26 | 26 | 9 | 10 | 4.78 | .296 | 1.26 | 8.0 | 3.3 | 3.7 | 192.0 | 170 | 110 | 102 | 20 | 71 | 79 | 5 | 0 | 0 | 0 | 11 | 1 | 3 | 4.66 |
| RP | Davis, W.Davis, Wade † >> | 29 | 2015 | R | 88 | 72 | 0 | 7 | 2 | 1.51 | .251 | 0.98 | 4.8 | 4.1 | 8.9 | 77.2 | 41 | 14 | 13 | 6 | 35 | 76 | 0 | 14 | 1 | 0 | 0 | 2 | 0 | 3.48 |
| RP | Gossage, R.Gossage, Rich >> | 30 | 1981 | R | 89 | 16 | 0 | 1 | 0 | 3.42 | .304 | 1.27 | 8.2 | 3.5 | 10.2 | 23.2 | 21 | 9 | 9 | 5 | 9 | 26 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 4.87 |
| RP | Benitez, A.Benitez, Armando >> | 32 | 2004 | R | 81 | 26 | 0 | 4 | 2 | 3.38 | .304 | 1.31 | 7.6 | 4.5 | 8.3 | 26.2 | 22 | 10 | 10 | 3 | 13 | 24 | 0 | 2 | 1 | 0 | 0 | 0 | 0 | 4.15 |
| RP | Hoffman, T.Hoffman, Trevor >> | 31 | 1998 | R | 75 | 35 | 0 | 4 | 2 | 4.99 | .339 | 1.51 | 9.7 | 4.2 | 7.6 | 39.2 | 42 | 22 | 22 | 4 | 18 | 33 | 0 | 2 | 1 | 0 | 0 | 1 | 3 | 4.10 |
| RP | Capps, C.Capps, Carter >> | 24 | 2015 | R | 84 | 31 | 0 | 3 | 1 | 4.91 | .371 | 1.74 | 8.7 | 7.1 | 9.6 | 29.1 | 28 | 18 | 16 | 7 | 23 | 31 | 0 | 2 | 0 | 0 | 0 | 1 | 1 | 6.48 |
| CL | Kimbrel, C.Kimbrel, Craig >> | 24 | 2012 | R | 100 | 56 | 0 | 2 | 6 | 2.96 | .301 | 1.28 | 7.1 | 4.4 | 10.9 | 79.0 | 62 | 26 | 26 | 11 | 39 | 96 | 0 | 11 | 4 | 0 | 0 | 1 | 2 | 3.90 |