| SP | Kershaw, C.Kershaw, Clayton >> | 28 | 2016 | L | 99 | 31 | 31 | 17 | 10 | 3.85 | .269 | 1.08 | 8.0 | 1.7 | 7.8 | 238.2 | 211 | 102 | 102 | 27 | 46 | 206 | 12 | 0 | 0 | 1 | 18 | 6 | 6 | 3.40 |
| SP | Mathewson, C.Mathewson, Christy >> | 28 | 1908 | R | 83 | 30 | 30 | 11 | 11 | 3.29 | .271 | 1.09 | 7.4 | 2.4 | 5.8 | 227.0 | 186 | 90 | 83 | 17 | 61 | 146 | 8 | 0 | 0 | 2 | 19 | 6 | 5 | 3.57 |
| SP | Chesbro, J.Chesbro, Jack # >> | 30 | 1904 | R | 65 | 30 | 30 | 8 | 17 | 5.68 | .340 | 1.52 | 10.7 | 3.0 | 4.4 | 210.2 | 249 | 141 | 133 | 44 | 71 | 103 | 9 | 0 | 0 | 1 | 11 | 5 | 4 | 5.83 |
| SP | Tudor, J.Tudor, John # >> | 31 | 1985 | L | 63 | 29 | 29 | 11 | 11 | 3.89 | .278 | 1.13 | 7.7 | 2.5 | 4.8 | 215.0 | 184 | 97 | 93 | 21 | 59 | 115 | 9 | 0 | 0 | 4 | 18 | 5 | 2 | 4.09 |
| SP | Hudson, D.Hudson, Daniel >> | 23 | 2010 | R | 60 | 28 | 27 | 9 | 8 | 5.60 | .330 | 1.47 | 9.1 | 4.1 | 6.4 | 164.0 | 166 | 114 | 102 | 24 | 75 | 117 | 1 | 0 | 0 | 0 | 11 | 1 | 2 | 4.87 |
| RP | Uehara, K.Uehara, Koji >> | 38 | 2013 | R | 100 | 70 | 0 | 6 | 3 | 2.77 | .266 | 1.04 | 6.5 | 2.9 | 8.0 | 91.0 | 66 | 28 | 28 | 8 | 29 | 81 | 0 | 5 | 4 | 0 | 0 | 4 | 0 | 3.45 |
| RP | Marmol, C.Marmol, Carlos † >> | 26 | 2008 | R | 71 | 55 | 0 | 8 | 4 | 3.68 | .288 | 1.20 | 6.1 | 4.6 | 7.8 | 66.0 | 45 | 28 | 27 | 6 | 34 | 57 | 0 | 8 | 2 | 0 | 0 | 1 | 2 | 4.05 |
| RP | Valverde, J.Valverde, Jose >> | 24 | 2003 | R | 64 | 38 | 0 | 4 | 4 | 3.09 | .292 | 1.21 | 6.1 | 5.0 | 8.6 | 43.2 | 29 | 16 | 15 | 5 | 24 | 41 | 0 | 1 | 3 | 0 | 0 | 1 | 2 | 4.35 |
| RP | Russell, J.Russell, Jeff >> | 28 | 1989 | R | 57 | 25 | 0 | 2 | 2 | 1.98 | .248 | 0.99 | 5.3 | 3.7 | 8.7 | 27.1 | 16 | 6 | 6 | 0 | 11 | 26 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 2.30 |
| RP | Perkins, G.Perkins, Glen >> | 30 | 2013 | L | 50 | 22 | 0 | 0 | 0 | 2.16 | .257 | 0.96 | 6.1 | 2.5 | 9.4 | 25.0 | 17 | 6 | 6 | 2 | 7 | 26 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 3.04 |
| SP | Overall, O.Overall, Orval >> | 28 | 1909 | R | 57 | 11 | 1 | 1 | 1 | 5.55 | .387 | 1.89 | 10.5 | 6.8 | 8.3 | 24.1 | 28 | 17 | 15 | 2 | 18 | 22 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 4.50 |