| SP | deGrom, J.deGrom, Jacob † >> | 33 | 2021 | R | 100 | 21 | 21 | 9 | 5 | 3.04 | .255 | 1.01 | 6.6 | 2.5 | 9.4 | 148.0 | 109 | 55 | 50 | 18 | 41 | 154 | 3 | 0 | 0 | 0 | 13 | 2 | 0 | 3.37 |
| SP | Brown, M.Brown, Mordecai >> | 32 | 1908 | R | 85 | 20 | 20 | 5 | 9 | 4.01 | .313 | 1.35 | 8.6 | 3.5 | 4.0 | 150.1 | 144 | 70 | 67 | 11 | 59 | 66 | 4 | 0 | 0 | 1 | 10 | 2 | 6 | 4.29 |
| SP | Waddell, R.Waddell, Rube >> | 29 | 1905 | L | 67 | 19 | 19 | 5 | 11 | 5.05 | .339 | 1.52 | 9.0 | 4.7 | 5.5 | 135.1 | 135 | 80 | 76 | 20 | 71 | 82 | 1 | 0 | 0 | 0 | 7 | 2 | 4 | 5.33 |
| RP | Gallegos, G.Gallegos, Giovanny >> | 27 | 2019 | R | 82 | 45 | 0 | 3 | 4 | 3.12 | .303 | 1.29 | 7.5 | 4.0 | 8.6 | 49.0 | 41 | 18 | 17 | 4 | 22 | 47 | 0 | 7 | 2 | 0 | 0 | 1 | 3 | 3.55 |
| RP | Sutter, B.Sutter, Bruce >> | 24 | 1977 | R | 67 | 23 | 0 | 3 | 2 | 4.26 | .296 | 1.26 | 8.1 | 3.5 | 9.9 | 31.2 | 28 | 15 | 15 | 2 | 12 | 34 | 0 | 4 | 0 | 0 | 0 | 0 | 1 | 2.81 |
| RP | Fingers, R.Fingers, Rollie >> | 35 | 1981 | R | 53 | 7 | 0 | 0 | 0 | 3.00 | .250 | 1.00 | 6.8 | 2.3 | 2.3 | 12.0 | 9 | 4 | 4 | 1 | 3 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.33 |
| SP | Drysdale, D.Drysdale, Don >> | 28 | 1964 | R | 59 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Harden, R.Harden, Rich >> | 27 | 2008 | R | 60 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |