| SP | Kershaw, C.Kershaw, Clayton # >> | 28 | 2016 | L | 99 | 27 | 27 | 12 | 10 | 3.48 | .270 | 1.10 | 8.7 | 1.2 | 7.9 | 209.1 | 202 | 86 | 81 | 23 | 28 | 184 | 6 | 0 | 0 | 2 | 19 | 2 | 5 | 3.10 |
| SP | Nelson, R.Nelson, Roger >> | 28 | 1972 | R | 84 | 26 | 26 | 3 | 13 | 5.67 | .345 | 1.56 | 10.4 | 3.7 | 6.2 | 131.2 | 151 | 92 | 83 | 17 | 54 | 90 | 0 | 0 | 0 | 0 | 3 | 3 | 3 | 4.62 |
| SP | Schmidt, J.Schmidt, Jason >> | 30 | 2003 | R | 67 | 24 | 24 | 9 | 10 | 4.85 | .328 | 1.47 | 10.2 | 3.0 | 7.2 | 169.0 | 191 | 99 | 91 | 27 | 57 | 135 | 3 | 0 | 0 | 0 | 12 | 0 | 4 | 4.49 |
| SP | Chesbro, J.Chesbro, Jack >> | 30 | 1904 | R | 65 | 25 | 25 | 4 | 13 | 5.50 | .340 | 1.50 | 10.0 | 3.5 | 4.7 | 176.2 | 196 | 118 | 108 | 24 | 69 | 92 | 8 | 0 | 0 | 1 | 7 | 8 | 7 | 5.04 |
| RP | Feliz, N.Feliz, Neftali † >> | 21 | 2009 | R | 97 | 63 | 0 | 7 | 4 | 2.92 | .294 | 1.23 | 6.8 | 4.4 | 8.1 | 101.2 | 76 | 34 | 33 | 9 | 49 | 91 | 0 | 3 | 4 | 0 | 0 | 2 | 0 | 3.87 |
| RP | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 85 | 56 | 0 | 3 | 7 | 4.28 | .294 | 1.19 | 8.9 | 2.0 | 7.4 | 73.2 | 72 | 38 | 35 | 9 | 16 | 60 | 0 | 9 | 3 | 0 | 0 | 4 | 0 | 3.78 |
| RP | Sutter, B.Sutter, Bruce # >> | 24 | 1977 | R | 67 | 46 | 0 | 4 | 2 | 4.57 | .341 | 1.55 | 9.7 | 4.3 | 7.9 | 65.0 | 70 | 36 | 33 | 11 | 31 | 57 | 0 | 6 | 4 | 0 | 0 | 0 | 3 | 4.88 |
| RP | Foulke, K.Foulke, Keith >> | 27 | 1999 | R | 59 | 25 | 0 | 2 | 2 | 4.17 | .304 | 1.28 | 9.5 | 2.3 | 7.3 | 36.2 | 38 | 17 | 17 | 8 | 9 | 29 | 0 | 2 | 1 | 0 | 0 | 1 | 0 | 5.11 |
| RP | Drabowsky, M.Drabowsky, Moe >> | 31 | 1966 | R | 53 | 24 | 0 | 2 | 1 | 5.23 | .306 | 1.33 | 8.8 | 3.1 | 8.4 | 43.0 | 42 | 26 | 25 | 10 | 15 | 40 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 5.21 |
| SP | Hudson, D.Hudson, Daniel >> | 23 | 2010 | R | 60 | 2 | 2 | 0 | 2 | 8.49 | .364 | 1.63 | 14.7 | 0.8 | 6.5 | 11.2 | 18 | 11 | 11 | 3 | 1 | 8 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 5.64 |
| SP | Liriano, F.Liriano, Francisco >> | 23 | 2006 | L | 58 | 4 | 0 | 0 | 0 | 2.08 | .278 | 1.15 | 6.8 | 4.5 | 4.5 | 4.1 | 3 | 1 | 1 | 1 | 2 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 6.75 |