| SP | deGrom, J.deGrom, Jacob >> | 33 | 2021 | R | 100 | 3 | 3 | 2 | 0 | 0.41 | .143 | 0.50 | 4.1 | 0.4 | 7.4 | 22.0 | 10 | 3 | 1 | 0 | 1 | 18 | 0 | 0 | 0 | 0 | 3 | 0 | 0 | 1.50 |
| SP | Arrieta, J.Arrieta, Jake >> | 29 | 2015 | R | 93 | 3 | 3 | 0 | 2 | 10.80 | .394 | 1.95 | 14.5 | 3.5 | 6.9 | 13.1 | 21 | 16 | 16 | 3 | 5 | 10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.62 |
| SP | McLain, D.McLain, Denny >> | 24 | 1968 | R | 78 | 3 | 3 | 0 | 1 | 5.00 | .316 | 1.39 | 8.5 | 4.0 | 3.0 | 18.0 | 17 | 11 | 10 | 0 | 8 | 6 | 0 | 0 | 0 | 0 | 2 | 0 | 1 | 3.67 |
| SP | Cicotte, E.Cicotte, Eddie >> | 33 | 1917 | R | 73 | 3 | 2 | 1 | 1 | 27.00 | .571 | 4.00 | 27.0 | 9.0 | 0.0 | 3.0 | 9 | 9 | 9 | 2 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 14.67 |
| SU | Chapman, A.Chapman, Aroldis >> | 26 | 2014 | L | 94 | 9 | 0 | 0 | 1 | 6.23 | .366 | 1.73 | 10.1 | 6.8 | 11.3 | 8.2 | 9 | 6 | 6 | 0 | 6 | 10 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 2.75 |
| CL | Eckersley, D.Eckersley, Dennis >> | 36 | 1990 | R | 88 | 7 | 0 | 1 | 0 | 3.75 | .357 | 1.58 | 11.3 | 3.0 | 6.8 | 12.0 | 15 | 6 | 5 | 0 | 4 | 9 | 0 | 2 | 0 | 0 | 0 | 1 | 0 | 2.75 |
| RP | Benitez, A.Benitez, Armando >> | 32 | 2004 | R | 82 | 8 | 0 | 0 | 0 | 3.86 | .375 | 1.80 | 13.1 | 4.1 | 2.5 | 11.2 | 16 | 5 | 5 | 1 | 5 | 3 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 5.00 |
| RP | Balfour, G.Balfour, Grant >> | 31 | 2008 | R | 76 | 8 | 0 | 0 | 1 | 6.30 | .400 | 2.00 | 12.6 | 5.4 | 10.8 | 10.0 | 14 | 13 | 7 | 1 | 6 | 12 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 3.70 |