| SP | Arrieta, J.Arrieta, Jake >> | 29 | 2015 | R | 93 | 21 | 21 | 7 | 7 | 3.33 | .261 | 1.03 | 7.2 | 2.2 | 6.7 | 137.2 | 109 | 53 | 51 | 11 | 33 | 102 | 1 | 0 | 0 | 0 | 13 | 4 | 1 | 3.36 |
| SP | Alexander, P.Alexander, Pete >> | 28 | 1915 | R | 88 | 20 | 20 | 9 | 6 | 3.01 | .263 | 1.05 | 7.1 | 2.3 | 4.5 | 131.2 | 104 | 49 | 44 | 14 | 34 | 65 | 2 | 0 | 0 | 1 | 12 | 3 | 2 | 4.24 |
| SP | Snell, B.Snell, Blake † >> | 25 | 2018 | L | 80 | 20 | 20 | 14 | 1 | 2.12 | .247 | 0.95 | 5.2 | 3.4 | 7.9 | 127.1 | 73 | 33 | 30 | 13 | 48 | 112 | 0 | 0 | 0 | 0 | 16 | 4 | 2 | 3.80 |
| SP | Fernandez, J.Fernandez, Jose † >> | 21 | 2013 | R | 76 | 20 | 19 | 13 | 2 | 2.60 | .277 | 1.15 | 7.0 | 3.3 | 7.5 | 142.0 | 111 | 44 | 41 | 13 | 52 | 118 | 1 | 0 | 0 | 1 | 16 | 0 | 1 | 3.63 |
| SP | Lincecum, T.Lincecum, Tim # >> | 25 | 2009 | R | 39 | 18 | 18 | 7 | 7 | 4.58 | .307 | 1.31 | 9.1 | 2.7 | 9.2 | 127.2 | 129 | 67 | 65 | 17 | 38 | 130 | 6 | 0 | 0 | 0 | 9 | 3 | 4 | 3.66 |
| RP | Kuo, H.Kuo, Hong-Chih † >> | 29 | 2010 | L | 91 | 45 | 0 | 5 | 1 | 2.73 | .255 | 1.03 | 5.9 | 3.5 | 9.0 | 52.2 | 34 | 16 | 16 | 2 | 20 | 52 | 0 | 10 | 0 | 0 | 0 | 0 | 3 | 2.65 |
| RP | Eckersley, D.Eckersley, Dennis >> | 36 | 1990 | R | 88 | 27 | 0 | 2 | 4 | 3.82 | .298 | 1.27 | 9.6 | 2.1 | 5.7 | 30.2 | 32 | 15 | 13 | 0 | 7 | 19 | 0 | 5 | 1 | 0 | 0 | 0 | 0 | 2.43 |
| RP | Devine, J.Devine, Joey >> | 25 | 2008 | R | 80 | 15 | 0 | 3 | 1 | 1.93 | .188 | 0.70 | 6.0 | 0.5 | 7.5 | 18.2 | 12 | 4 | 4 | 2 | 1 | 15 | 0 | 2 | 1 | 0 | 0 | 0 | 0 | 2.94 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 75 | 3 | 0 | 0 | 0 | 4.50 | .294 | 1.25 | 4.5 | 6.8 | 4.5 | 4.0 | 2 | 2 | 2 | 0 | 3 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.25 |
| RP | Eichhorn, M.Eichhorn, Mark >> | 26 | 1986 | R | 48 | 17 | 0 | 0 | 0 | 5.28 | .336 | 1.52 | 8.4 | 5.3 | 9.0 | 29.0 | 27 | 17 | 17 | 4 | 17 | 29 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.55 |