| SP | Maddux, G.Maddux, Greg † >> | 34 | 2000 | R | 95 | 30 | 30 | 12 | 10 | 3.46 | .292 | 1.21 | 8.1 | 2.8 | 6.3 | 234.0 | 211 | 92 | 90 | 28 | 72 | 164 | 6 | 0 | 0 | 2 | 18 | 6 | 2 | 4.15 |
| SP | Mussina, M.Mussina, Mike >> | 32 | 2000 | R | 86 | 28 | 28 | 11 | 10 | 3.72 | .293 | 1.21 | 8.2 | 2.6 | 5.8 | 213.0 | 195 | 92 | 88 | 31 | 62 | 138 | 2 | 0 | 0 | 0 | 16 | 8 | 4 | 4.58 |
| SP | Abbott, P.Abbott, Paul >> | 33 | 2000 | R | 65 | 28 | 28 | 8 | 13 | 4.40 | .320 | 1.40 | 8.8 | 3.8 | 5.6 | 153.1 | 149 | 80 | 75 | 22 | 65 | 95 | 0 | 0 | 0 | 0 | 9 | 2 | 3 | 4.94 |
| SP | Politte, C.Politte, Cliff >> | 26 | 2000 | R | 64 | 27 | 27 | 9 | 7 | 5.14 | .342 | 1.55 | 9.3 | 4.6 | 7.0 | 138.1 | 143 | 82 | 79 | 18 | 71 | 107 | 0 | 0 | 0 | 0 | 5 | 2 | 7 | 4.73 |
| RP | Sasaki, K.Sasaki, Kazuhiro # >> | 32 | 2000 | R | 95 | 74 | 0 | 5 | 4 | 4.66 | .307 | 1.32 | 6.5 | 5.5 | 8.4 | 92.2 | 66 | 53 | 48 | 8 | 56 | 86 | 0 | 7 | 4 | 0 | 0 | 1 | 1 | 4.12 |
| RP | Garces, R.Garces, Rich # >> | 29 | 2000 | R | 81 | 66 | 0 | 8 | 6 | 4.97 | .337 | 1.49 | 9.2 | 4.1 | 8.2 | 76.0 | 78 | 46 | 42 | 15 | 35 | 69 | 0 | 3 | 3 | 0 | 0 | 3 | 1 | 5.25 |
| RP | Paniagua, J.Paniagua, Jose >> | 27 | 2000 | R | 58 | 30 | 0 | 3 | 0 | 3.18 | .261 | 1.00 | 6.9 | 2.1 | 9.5 | 34.0 | 26 | 12 | 12 | 6 | 8 | 36 | 0 | 5 | 2 | 0 | 0 | 2 | 2 | 4.06 |
| RP | Mantei, M.Mantei, Matt >> | 27 | 2000 | R | 50 | 15 | 0 | 0 | 1 | 1.17 | .313 | 1.30 | 5.4 | 6.6 | 7.2 | 15.1 | 9 | 2 | 2 | 1 | 11 | 12 | 0 | 2 | 0 | 0 | 0 | 1 | 0 | 4.67 |
| RP | Williamson, S.Williamson, Scott >> | 24 | 2000 | R | 37 | 27 | 0 | 0 | 0 | 2.74 | .270 | 1.09 | 5.7 | 4.1 | 8.0 | 46.0 | 29 | 14 | 14 | 3 | 21 | 41 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 3.50 |
| SP | Miller, W.Miller, Wade >> | 24 | 2000 | R | 62 | 2 | 1 | 1 | 1 | 4.05 | .375 | 1.80 | 12.0 | 6.0 | 3.0 | 6.2 | 8 | 3 | 3 | 0 | 4 | 2 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 4.33 |