| SP | Johnson, R.Johnson, Randy † >> | 37 | 2000 | L | 99 | 21 | 21 | 12 | 3 | 2.37 | .275 | 1.12 | 6.6 | 3.5 | 9.9 | 148.1 | 109 | 41 | 39 | 13 | 57 | 163 | 3 | 0 | 0 | 3 | 17 | 3 | 1 | 3.16 |
| SP | Clemens, R.Clemens, Roger >> | 38 | 2000 | R | 83 | 21 | 21 | 5 | 11 | 4.05 | .321 | 1.39 | 8.9 | 3.7 | 7.1 | 135.2 | 133 | 63 | 61 | 19 | 56 | 107 | 1 | 0 | 0 | 0 | 13 | 3 | 2 | 4.56 |
| SP | Hampton, M.Hampton, Mike >> | 28 | 2000 | L | 77 | 20 | 20 | 6 | 5 | 6.65 | .369 | 1.72 | 10.6 | 4.9 | 6.0 | 108.1 | 127 | 84 | 80 | 14 | 59 | 72 | 0 | 0 | 0 | 0 | 6 | 4 | 3 | 5.10 |
| SP | Colon, B.Colon, Bartolo >> | 27 | 2000 | R | 69 | 20 | 20 | 8 | 5 | 3.37 | .301 | 1.28 | 6.8 | 4.8 | 10.2 | 128.1 | 96 | 52 | 48 | 9 | 68 | 145 | 0 | 0 | 0 | 0 | 12 | 2 | 4 | 3.29 |
| CL | Benitez, A.Benitez, Armando † >> | 28 | 2000 | R | 99 | 51 | 0 | 3 | 4 | 3.84 | .282 | 1.13 | 6.7 | 3.6 | 11.2 | 58.2 | 43 | 26 | 25 | 2 | 23 | 72 | 0 | 17 | 4 | 0 | 0 | 3 | 0 | 2.31 |
| RP | Remlinger, M.Remlinger, Mike >> | 34 | 2000 | L | 82 | 59 | 0 | 2 | 3 | 6.97 | .397 | 1.93 | 12.3 | 5.3 | 9.5 | 60.2 | 82 | 50 | 47 | 15 | 35 | 63 | 0 | 4 | 7 | 0 | 0 | 3 | 3 | 6.05 |
| RP | Rodriguez, F.Rodriguez, Felix >> | 28 | 2000 | R | 71 | 56 | 0 | 7 | 3 | 4.21 | .307 | 1.24 | 7.1 | 4.1 | 9.4 | 66.1 | 52 | 31 | 31 | 8 | 30 | 69 | 0 | 3 | 2 | 0 | 0 | 6 | 4 | 4.12 |
| RP | Guardado, E.Guardado, Eddie >> | 30 | 2000 | L | 59 | 45 | 0 | 7 | 1 | 3.15 | .288 | 1.21 | 7.3 | 3.7 | 7.7 | 54.1 | 44 | 21 | 19 | 9 | 22 | 46 | 0 | 2 | 2 | 0 | 0 | 0 | 0 | 4.69 |
| RP | Wickman, B.Wickman, Bob >> | 31 | 2000 | R | 53 | 43 | 0 | 1 | 1 | 3.74 | .325 | 1.45 | 8.0 | 5.2 | 7.8 | 45.2 | 40 | 19 | 19 | 6 | 26 | 39 | 0 | 3 | 2 | 0 | 0 | 0 | 0 | 4.73 |