| SP | Skubal, T.Skubal, Tarik † $ >> | 28 | 2025 | L | 100 | 28 | 28 | 19 | 5 | 2.17 | .272 | 1.10 | 7.6 | 2.3 | 10.3 | 190.2 | 161 | 47 | 46 | 15 | 49 | 217 | 1 | 0 | 0 | 0 | 25 | 4 | 4 | 2.58 |
| SP | Rogers, T.Rogers, Trevor $ >> | 27 | 2025 | L | 97 | 27 | 27 | 13 | 7 | 3.61 | .269 | 1.09 | 7.6 | 2.3 | 7.6 | 179.2 | 151 | 81 | 72 | 23 | 45 | 151 | 4 | 0 | 0 | 3 | 18 | 2 | 0 | 3.77 |
| SP | Yamamoto, Y.Yamamoto, Yoshinobu † $ >> | 26 | 2025 | R | 96 | 27 | 27 | 13 | 3 | 2.70 | .293 | 1.22 | 6.8 | 4.2 | 9.8 | 163.1 | 124 | 52 | 49 | 9 | 76 | 178 | 0 | 0 | 0 | 0 | 15 | 3 | 4 | 2.99 |
| SP | Brown, H.Brown, Hunter $ >> | 26 | 2025 | R | 93 | 26 | 26 | 11 | 5 | 3.62 | .302 | 1.28 | 8.5 | 3.0 | 10.1 | 154.1 | 146 | 67 | 62 | 15 | 52 | 173 | 1 | 0 | 0 | 1 | 14 | 2 | 0 | 3.07 |
| RP | Svanson, M.Svanson, Matt † >> | 26 | 2025 | R | 97 | 79 | 0 | 8 | 2 | 2.74 | .274 | 1.12 | 6.1 | 4.0 | 11.8 | 101.2 | 69 | 32 | 31 | 10 | 45 | 132 | 0 | 10 | 3 | 0 | 0 | 1 | 1 | 3.04 |
| RP | Fisher, B.Fisher, Braydon # >> | 24 | 2025 | R | 89 | 66 | 0 | 5 | 2 | 3.51 | .283 | 1.14 | 7.0 | 3.3 | 9.7 | 77.0 | 60 | 31 | 30 | 11 | 28 | 83 | 0 | 11 | 5 | 0 | 0 | 3 | 0 | 3.91 |
| RP | Saalfrank, A.Saalfrank, Andrew >> | 27 | 2025 | L | 81 | 84 | 0 | 1 | 3 | 3.21 | .231 | 0.84 | 4.6 | 3.1 | 7.8 | 53.1 | 27 | 22 | 19 | 9 | 18 | 46 | 0 | 2 | 5 | 0 | 0 | 3 | 2 | 4.66 |
| RP | O'Brien, R.O'Brien, Riley >> | 30 | 2025 | R | 68 | 33 | 0 | 1 | 2 | 4.97 | .397 | 1.93 | 9.4 | 8.3 | 7.2 | 25.1 | 26 | 17 | 14 | 3 | 23 | 20 | 0 | 5 | 4 | 0 | 0 | 1 | 3 | 5.84 |
| RP | Rodríguez, Y.Rodríguez, Yariel >> | 28 | 2025 | R | 66 | 23 | 0 | 2 | 5 | 5.73 | .327 | 1.45 | 8.6 | 4.5 | 8.6 | 22.0 | 21 | 14 | 14 | 1 | 11 | 21 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 3.18 |
| RP | Estrada, J.Estrada, Jeremiah >> | 26 | 2025 | R | 63 | 28 | 0 | 1 | 1 | 3.56 | .331 | 1.45 | 9.3 | 3.9 | 10.8 | 30.1 | 31 | 13 | 12 | 5 | 13 | 36 | 0 | 2 | 0 | 0 | 0 | 1 | 1 | 4.17 |