| SP | Skubal, T.Skubal, Tarik $$ >> | 28 | 2025 | L | 100 | 18 | 18 | 7 | 7 | 3.79 | .282 | 1.15 | 7.7 | 2.7 | 9.0 | 118.2 | 101 | 53 | 50 | 13 | 36 | 118 | 0 | 0 | 0 | 0 | 12 | 3 | 2 | 3.42 |
| SP | Rogers, T.Rogers, Trevor $$ >> | 27 | 2025 | L | 97 | 18 | 18 | 8 | 3 | 3.85 | .290 | 1.16 | 7.0 | 3.6 | 8.8 | 119.1 | 92 | 54 | 51 | 15 | 47 | 117 | 2 | 0 | 0 | 0 | 8 | 7 | 0 | 4.03 |
| SP | Yamamoto, Y.Yamamoto, Yoshinobu $$ >> | 26 | 2025 | R | 96 | 17 | 17 | 7 | 4 | 3.80 | .295 | 1.24 | 7.4 | 3.7 | 8.6 | 104.1 | 86 | 46 | 44 | 11 | 43 | 99 | 0 | 0 | 0 | 0 | 11 | 2 | 4 | 3.77 |
| SP | Brown, H.Brown, Hunter † $$ >> | 26 | 2025 | R | 93 | 17 | 17 | 12 | 1 | 2.53 | .277 | 1.12 | 6.3 | 3.8 | 10.2 | 110.1 | 77 | 33 | 31 | 9 | 47 | 125 | 1 | 0 | 0 | 1 | 10 | 3 | 0 | 3.15 |
| SP | Pérez, E.Pérez, Eury † >> | 22 | 2025 | R | 90 | 17 | 17 | 8 | 2 | 3.43 | .293 | 1.24 | 7.3 | 3.9 | 7.7 | 89.1 | 72 | 35 | 34 | 14 | 39 | 76 | 0 | 0 | 0 | 0 | 2 | 0 | 3 | 4.65 |
| RP | Chapman, A.Chapman, Aroldis >> | 37 | 2025 | L | 100 | 53 | 0 | 6 | 0 | 2.33 | .261 | 0.99 | 5.3 | 3.7 | 7.4 | 46.1 | 27 | 15 | 12 | 4 | 19 | 38 | 0 | 1 | 1 | 0 | 0 | 3 | 1 | 3.91 |
| RP | Fisher, B.Fisher, Braydon >> | 24 | 2025 | R | 89 | 45 | 0 | 4 | 1 | 3.93 | .325 | 1.39 | 7.1 | 5.5 | 11.4 | 52.2 | 41 | 25 | 23 | 4 | 32 | 66 | 0 | 0 | 5 | 0 | 0 | 3 | 0 | 3.48 |
| RP | Bautista, F.Bautista, Félix >> | 30 | 2025 | R | 83 | 38 | 0 | 4 | 4 | 3.89 | .309 | 1.32 | 6.3 | 5.5 | 11.0 | 44.0 | 31 | 19 | 19 | 3 | 27 | 54 | 0 | 5 | 2 | 0 | 0 | 1 | 3 | 3.34 |
| RP | Bazardo, E.Bazardo, Eduard # >> | 29 | 2025 | R | 85 | 35 | 0 | 3 | 3 | 4.65 | .316 | 1.35 | 7.8 | 4.4 | 8.4 | 31.0 | 27 | 16 | 16 | 5 | 15 | 29 | 0 | 3 | 1 | 0 | 0 | 1 | 0 | 4.77 |
| RP | Henriquez, R.Henriquez, Ronny >> | 25 | 2025 | R | 76 | 26 | 0 | 1 | 0 | 2.49 | .224 | 0.83 | 5.4 | 2.2 | 11.2 | 25.1 | 15 | 7 | 7 | 2 | 6 | 31 | 0 | 6 | 0 | 0 | 0 | 1 | 0 | 2.40 |
| RP | Rodríguez, Y.Rodríguez, Yariel >> | 28 | 2025 | R | 66 | 19 | 0 | 0 | 1 | 2.84 | .269 | 1.11 | 5.7 | 4.3 | 7.1 | 19.0 | 12 | 6 | 6 | 1 | 9 | 15 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 3.53 |
| RP | Hoffman, J.Hoffman, Jeff >> | 32 | 2025 | R | 58 | 20 | 0 | 0 | 1 | 3.63 | .309 | 1.30 | 9.4 | 2.5 | 12.3 | 22.1 | 23 | 9 | 9 | 3 | 6 | 30 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 3.00 |