| SP | Jimenez, U.Jimenez, Ubaldo >> | 26 | 2010 | R | 69 | 30 | 30 | 12 | 10 | 3.77 | .324 | 1.43 | 8.3 | 4.6 | 6.8 | 196.0 | 181 | 87 | 82 | 16 | 100 | 147 | 2 | 0 | 0 | 1 | 14 | 1 | 6 | 4.11 |
| SP | Chacin, J.Chacin, Jhoulys >> | 22 | 2010 | R | 43 | 30 | 30 | 9 | 9 | 4.06 | .303 | 1.29 | 7.1 | 4.6 | 7.4 | 148.2 | 116 | 69 | 67 | 9 | 76 | 121 | 0 | 0 | 0 | 0 | 8 | 2 | 1 | 3.74 |
| SP | Morales, F.Morales, Franklin >> | 21 | 2007 | L | 39 | 30 | 30 | 8 | 10 | 4.74 | .317 | 1.37 | 9.4 | 3.0 | 6.1 | 142.1 | 148 | 75 | 75 | 26 | 47 | 97 | 0 | 0 | 0 | 0 | 7 | 3 | 0 | 5.07 |
| SP | Francis, J.Francis, Jeff >> | 26 | 2007 | L | 18 | 30 | 29 | 9 | 12 | 4.70 | .318 | 1.39 | 9.8 | 2.8 | 6.6 | 168.1 | 182 | 92 | 88 | 22 | 52 | 124 | 2 | 0 | 0 | 1 | 14 | 1 | 1 | 4.17 |
| CL | Ottavino, A.Ottavino, Adam >> | 32 | 2018 | R | 83 | 65 | 0 | 7 | 4 | 3.50 | .323 | 1.39 | 7.9 | 4.6 | 10.6 | 72.0 | 63 | 29 | 28 | 9 | 37 | 85 | 0 | 18 | 7 | 0 | 0 | 3 | 2 | 3.93 |
| RP | Herges, M.Herges, Matt >> | 37 | 2007 | R | 59 | 99 | 0 | 3 | 3 | 4.48 | .299 | 1.26 | 7.9 | 3.5 | 6.3 | 122.2 | 107 | 61 | 61 | 21 | 47 | 85 | 0 | 5 | 3 | 0 | 0 | 3 | 0 | 5.07 |
| RP | Corpas, M.Corpas, Manuel >> | 25 | 2007 | R | 50 | 88 | 0 | 2 | 5 | 3.68 | .279 | 1.14 | 7.5 | 2.8 | 4.9 | 93.0 | 77 | 40 | 38 | 5 | 29 | 51 | 0 | 1 | 3 | 0 | 0 | 2 | 0 | 3.60 |
| RP | Hawkins, L.Hawkins, LaTroy >> | 35 | 2007 | R | 31 | 73 | 0 | 7 | 4 | 4.68 | .330 | 1.43 | 9.9 | 3.1 | 6.2 | 84.2 | 92 | 45 | 44 | 12 | 29 | 58 | 0 | 4 | 2 | 0 | 0 | 4 | 3 | 4.65 |
| RP | Fuentes, B.Fuentes, Brian >> | 32 | 2007 | L | 50 | 85 | 0 | 2 | 2 | 3.54 | .294 | 1.24 | 7.0 | 4.2 | 7.4 | 86.1 | 67 | 35 | 34 | 8 | 40 | 71 | 0 | 1 | 4 | 0 | 0 | 1 | 6 | 3.99 |
| RP | Affeldt, J.Affeldt, Jeremy >> | 28 | 2007 | L | 33 | 85 | 0 | 4 | 5 | 4.71 | .332 | 1.48 | 9.2 | 4.2 | 5.3 | 78.1 | 80 | 42 | 41 | 8 | 36 | 46 | 0 | 2 | 3 | 0 | 0 | 1 | 5 | 4.58 |