| SP | Santana, J.Santana, Johan >> | 27 | 2006 | L | 85 | 30 | 30 | 15 | 8 | 3.10 | .273 | 1.10 | 7.8 | 2.1 | 9.1 | 218.0 | 190 | 78 | 75 | 21 | 50 | 220 | 1 | 0 | 0 | 1 | 19 | 5 | 2 | 2.99 |
| SP | Liriano, F.Liriano, Francisco >> | 23 | 2006 | L | 92 | 30 | 30 | 6 | 6 | 3.41 | .265 | 1.08 | 7.1 | 2.7 | 9.4 | 148.0 | 116 | 59 | 56 | 17 | 44 | 155 | 0 | 0 | 0 | 0 | 2 | 0 | 4 | 3.29 |
| SP | Blyleven, B.Blyleven, Bert >> | 21 | 1972 | R | 59 | 29 | 29 | 13 | 11 | 5.00 | .316 | 1.36 | 9.1 | 3.2 | 7.0 | 208.2 | 210 | 119 | 116 | 37 | 74 | 162 | 6 | 0 | 0 | 1 | 10 | 5 | 3 | 4.89 |
| SP | Bonser, B.Bonser, Boof >> | 25 | 2006 | R | 30 | 29 | 29 | 8 | 12 | 5.34 | .322 | 1.39 | 10.3 | 2.2 | 7.5 | 167.0 | 191 | 101 | 99 | 23 | 41 | 140 | 0 | 0 | 0 | 0 | 13 | 6 | 3 | 3.96 |
| RP | Reyes, D.Reyes, Dennys >> | 29 | 2006 | L | 67 | 74 | 0 | 6 | 5 | 3.95 | .313 | 1.35 | 8.1 | 4.1 | 7.5 | 84.1 | 76 | 38 | 37 | 12 | 38 | 70 | 0 | 5 | 5 | 0 | 0 | 1 | 7 | 4.58 |
| RP | Aguilera, R.Aguilera, Rick >> | 30 | 1991 | R | 63 | 46 | 0 | 1 | 4 | 4.59 | .317 | 1.35 | 6.2 | 6.0 | 7.8 | 51.0 | 35 | 27 | 26 | 5 | 34 | 44 | 0 | 0 | 2 | 0 | 0 | 2 | 4 | 4.67 |
| RP | Rincon, J.Rincon, Juan >> | 27 | 2006 | R | 22 | 33 | 0 | 4 | 1 | 6.48 | .375 | 1.77 | 11.5 | 4.6 | 7.4 | 33.1 | 42 | 24 | 24 | 5 | 17 | 27 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 4.97 |