| SP | Verlander, J.Verlander, Justin >> | 36 | 2019 | R | 99 | 31 | 31 | 7 | 12 | 4.35 | .308 | 1.30 | 9.0 | 2.7 | 8.5 | 196.1 | 197 | 100 | 95 | 32 | 59 | 185 | 3 | 0 | 0 | 0 | 13 | 6 | 3 | 4.23 |
| SP | Greinke, Z.Greinke, Zack >> | 32 | 2015 | R | 94 | 30 | 30 | 11 | 10 | 4.00 | .301 | 1.28 | 8.7 | 2.8 | 6.0 | 202.2 | 196 | 103 | 90 | 19 | 63 | 135 | 3 | 0 | 0 | 2 | 16 | 3 | 7 | 3.87 |
| SP | Nelson, R.Nelson, Roger >> | 28 | 1972 | R | 85 | 30 | 30 | 1 | 20 | 7.43 | .370 | 1.73 | 13.2 | 2.5 | 5.6 | 135.2 | 198 | 121 | 112 | 22 | 37 | 84 | 0 | 0 | 0 | 0 | 3 | 4 | 4 | 4.79 |
| SP | McLain, D.McLain, Denny # >> | 24 | 1968 | R | 79 | 29 | 28 | 12 | 13 | 4.93 | .314 | 1.33 | 9.5 | 2.6 | 5.1 | 189.2 | 199 | 114 | 104 | 27 | 54 | 108 | 11 | 0 | 0 | 1 | 11 | 8 | 5 | 4.70 |
| RP | Doolittle, S.Doolittle, Sean >> | 31 | 2018 | L | 99 | 73 | 0 | 4 | 7 | 2.65 | .266 | 1.07 | 7.3 | 2.4 | 7.8 | 98.2 | 80 | 34 | 29 | 12 | 26 | 85 | 0 | 6 | 1 | 0 | 0 | 1 | 0 | 3.68 |
| RP | Feliz, N.Feliz, Neftali >> | 21 | 2009 | R | 97 | 66 | 0 | 4 | 1 | 3.38 | .315 | 1.37 | 8.5 | 3.9 | 8.3 | 74.2 | 70 | 33 | 28 | 9 | 32 | 68 | 0 | 6 | 2 | 0 | 0 | 1 | 0 | 4.08 |
| RP | Jansen, K.Jansen, Kenley >> | 28 | 2016 | R | 97 | 54 | 0 | 3 | 4 | 2.69 | .236 | 0.93 | 6.9 | 1.6 | 9.9 | 63.2 | 48 | 26 | 19 | 9 | 11 | 69 | 0 | 8 | 1 | 0 | 0 | 0 | 2 | 3.19 |
| RP | Benoit, J.Benoit, Joaquin # >> | 33 | 2010 | R | 95 | 38 | 0 | 1 | 3 | 4.74 | .295 | 1.24 | 8.6 | 2.6 | 7.2 | 49.1 | 47 | 30 | 26 | 7 | 14 | 39 | 0 | 3 | 2 | 0 | 0 | 1 | 1 | 4.18 |
| SP | Caldwell, R.Caldwell, Ray >> | 26 | 1914 | R | 64 | 18 | 0 | 2 | 3 | 5.40 | .371 | 1.73 | 12.0 | 3.6 | 3.0 | 30.0 | 40 | 22 | 18 | 7 | 12 | 10 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 6.67 |