| SP | Martinez, P.Martinez, Pedro >> | 29 | 2000 | R | 100 | 23 | 23 | 9 | 9 | 4.44 | .314 | 1.35 | 9.9 | 2.3 | 8.4 | 162.0 | 178 | 84 | 80 | 24 | 41 | 152 | 4 | 0 | 0 | 0 | 10 | 3 | 4 | 3.86 |
| SP | Snell, B.Snell, Blake # >> | 25 | 2018 | L | 80 | 22 | 22 | 12 | 7 | 4.66 | .332 | 1.45 | 9.1 | 4.0 | 7.9 | 123.2 | 124 | 65 | 64 | 11 | 55 | 108 | 0 | 0 | 0 | 0 | 9 | 5 | 5 | 3.87 |
| SP | McLain, D.McLain, Denny >> | 24 | 1968 | R | 78 | 22 | 22 | 12 | 8 | 4.59 | .315 | 1.36 | 9.5 | 2.8 | 6.1 | 158.2 | 166 | 85 | 81 | 17 | 50 | 107 | 6 | 0 | 0 | 0 | 10 | 3 | 3 | 4.05 |
| CL | Chapman, A.Chapman, Aroldis >> | 26 | 2014 | L | 93 | 38 | 0 | 2 | 1 | 3.05 | .287 | 1.21 | 6.6 | 4.4 | 10.1 | 41.1 | 30 | 14 | 14 | 6 | 20 | 46 | 0 | 22 | 5 | 0 | 0 | 0 | 3 | 4.12 |
| SU | Saito, T.Saito, Takashi >> | 37 | 2007 | R | 91 | 47 | 0 | 2 | 1 | 3.88 | .322 | 1.43 | 9.0 | 3.9 | 8.5 | 53.1 | 53 | 23 | 23 | 4 | 23 | 50 | 0 | 3 | 1 | 0 | 0 | 0 | 0 | 3.40 |
| RP | Percival, T.Percival, Troy >> | 26 | 1995 | R | 82 | 49 | 0 | 1 | 0 | 5.19 | .344 | 1.56 | 9.5 | 4.6 | 9.2 | 59.0 | 62 | 37 | 34 | 8 | 30 | 60 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 4.31 |
| RP | Balfour, G.Balfour, Grant >> | 31 | 2008 | R | 75 | 46 | 0 | 4 | 6 | 3.20 | .347 | 1.58 | 9.0 | 5.2 | 7.8 | 59.0 | 59 | 24 | 21 | 4 | 34 | 51 | 0 | 0 | 0 | 0 | 0 | 1 | 3 | 3.93 |
| RP | Dotel, O.Dotel, Octavio >> | 29 | 2002 | R | 69 | 36 | 0 | 2 | 2 | 4.81 | .372 | 1.78 | 9.2 | 6.9 | 7.6 | 39.1 | 40 | 25 | 21 | 3 | 30 | 33 | 0 | 3 | 1 | 0 | 0 | 0 | 1 | 4.62 |
| RP | Urbina, U.Urbina, Ugueth >> | 24 | 1998 | R | 58 | 30 | 0 | 1 | 0 | 4.28 | .299 | 1.25 | 7.6 | 3.8 | 9.8 | 33.2 | 28 | 19 | 16 | 2 | 14 | 36 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 2.97 |