| SP | Martinez, P.Martinez, Pedro >> | 29 | 2000 | R | 100 | 32 | 32 | 13 | 11 | 3.10 | .285 | 1.18 | 8.1 | 2.6 | 8.7 | 229.0 | 205 | 87 | 79 | 25 | 65 | 222 | 6 | 0 | 0 | 2 | 23 | 4 | 1 | 3.38 |
| SP | Arrieta, J.Arrieta, Jake >> | 29 | 2015 | R | 92 | 34 | 34 | 7 | 14 | 5.27 | .349 | 1.56 | 10.4 | 3.6 | 7.0 | 205.0 | 237 | 127 | 120 | 28 | 82 | 160 | 2 | 0 | 0 | 0 | 15 | 10 | 5 | 4.56 |
| RP | Boxberger, B.Boxberger, Brad >> | 26 | 2014 | R | 83 | 81 | 0 | 3 | 3 | 4.32 | .304 | 1.30 | 6.9 | 4.9 | 10.1 | 93.2 | 71 | 48 | 45 | 12 | 51 | 104 | 0 | 3 | 0 | 0 | 0 | 1 | 3 | 4.12 |
| RP | Treinen, B.Treinen, Blake >> | 30 | 2018 | R | 80 | 65 | 0 | 3 | 4 | 5.38 | .317 | 1.39 | 8.3 | 4.3 | 7.9 | 75.1 | 69 | 46 | 45 | 8 | 36 | 66 | 0 | 2 | 2 | 0 | 0 | 0 | 4 | 4.07 |
| RP | Hoffman, T.Hoffman, Trevor >> | 31 | 1998 | R | 75 | 49 | 0 | 1 | 3 | 4.06 | .322 | 1.38 | 9.1 | 3.4 | 8.3 | 68.2 | 69 | 32 | 31 | 5 | 26 | 63 | 0 | 0 | 0 | 0 | 0 | 3 | 7 | 3.38 |
| CL | Jansen, K.Jansen, Kenley † >> | 28 | 2016 | R | 97 | 67 | 0 | 6 | 4 | 3.56 | .288 | 1.21 | 8.0 | 3.0 | 10.2 | 73.1 | 65 | 30 | 29 | 7 | 24 | 83 | 0 | 31 | 6 | 0 | 0 | 0 | 1 | 2.96 |