| SP | Greinke, Z.Greinke, Zack >> | 32 | 2015 | R | 94 | 32 | 32 | 11 | 15 | 4.46 | .324 | 1.42 | 10.1 | 2.7 | 5.7 | 218.0 | 244 | 116 | 108 | 22 | 66 | 137 | 4 | 0 | 0 | 0 | 15 | 3 | 6 | 4.00 |
| SP | Hernandez, F.Hernandez, Felix # >> | 28 | 2014 | R | 79 | 31 | 31 | 11 | 10 | 4.59 | .304 | 1.29 | 8.9 | 2.7 | 8.0 | 206.0 | 203 | 112 | 105 | 31 | 62 | 183 | 4 | 0 | 0 | 0 | 17 | 5 | 6 | 4.16 |
| SP | Clemens, R.Clemens, Roger >> | 24 | 1986 | R | 69 | 31 | 31 | 9 | 14 | 6.25 | .348 | 1.56 | 10.0 | 4.0 | 5.6 | 198.2 | 221 | 142 | 138 | 40 | 89 | 123 | 6 | 0 | 0 | 0 | 7 | 8 | 6 | 5.85 |
| SP | Hudson, D.Hudson, Daniel >> | 23 | 2010 | R | 60 | 29 | 29 | 5 | 18 | 4.79 | .305 | 1.32 | 8.8 | 3.1 | 6.0 | 182.1 | 178 | 98 | 97 | 19 | 62 | 121 | 2 | 0 | 0 | 2 | 15 | 0 | 8 | 4.05 |
| RP | Benoit, J.Benoit, Joaquin >> | 33 | 2010 | R | 95 | 83 | 0 | 5 | 6 | 4.32 | .317 | 1.37 | 8.6 | 3.8 | 8.7 | 106.1 | 101 | 52 | 51 | 10 | 45 | 102 | 0 | 10 | 7 | 0 | 0 | 2 | 5 | 3.63 |
| RP | Williams, D.Williams, Devin >> | 28 | 2023 | R | 72 | 68 | 0 | 3 | 5 | 4.95 | .318 | 1.39 | 6.9 | 5.6 | 7.7 | 80.0 | 61 | 44 | 44 | 9 | 50 | 68 | 0 | 8 | 2 | 0 | 0 | 1 | 2 | 4.68 |
| SP | Cuellar, M.Cuellar, Mike >> | 32 | 1969 | L | 43 | 2 | 0 | 0 | 0 | 8.10 | .524 | 3.30 | 27.0 | 6.0 | 6.0 | 3.1 | 9 | 6 | 3 | 0 | 2 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.67 |
| SP | Saberhagen, B.Saberhagen, Bret >> | 25 | 1989 | R | 50 | 11 | 0 | 1 | 1 | 6.57 | .321 | 1.38 | 10.1 | 2.6 | 3.0 | 24.2 | 27 | 20 | 18 | 4 | 7 | 8 | 0 | 3 | 0 | 0 | 0 | 1 | 0 | 5.50 |