| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 95 | 32 | 32 | 7 | 14 | 5.76 | .346 | 1.57 | 9.8 | 4.5 | 8.6 | 190.2 | 206 | 130 | 122 | 24 | 94 | 181 | 1 | 0 | 0 | 0 | 12 | 2 | 5 | 4.25 |
| SP | Hughes, T.Hughes, Tom # >> | 31 | 1915 | R | 62 | 31 | 31 | 9 | 16 | 6.23 | .361 | 1.68 | 12.0 | 3.2 | 5.1 | 151.2 | 202 | 114 | 105 | 31 | 53 | 85 | 0 | 0 | 0 | 0 | 6 | 2 | 0 | 5.64 |
| SP | Coveleski, S.Coveleski, Stan # >> | 28 | 1917 | R | 61 | 31 | 31 | 11 | 9 | 4.95 | .333 | 1.48 | 9.3 | 4.0 | 4.6 | 182.0 | 189 | 106 | 100 | 24 | 81 | 94 | 0 | 0 | 0 | 0 | 9 | 2 | 2 | 5.05 |
| SP | Tanana, F.Tanana, Frank >> | 23 | 1976 | L | 58 | 31 | 29 | 13 | 13 | 5.06 | .336 | 1.49 | 10.3 | 3.2 | 6.1 | 199.1 | 227 | 119 | 112 | 32 | 71 | 135 | 8 | 0 | 0 | 1 | 12 | 4 | 2 | 4.86 |
| RP | Street, H.Street, Huston † >> | 29 | 2012 | R | 96 | 86 | 0 | 6 | 4 | 3.14 | .270 | 1.08 | 6.3 | 3.5 | 7.7 | 117.1 | 82 | 44 | 41 | 16 | 45 | 100 | 0 | 8 | 2 | 0 | 0 | 3 | 3 | 4.30 |
| RP | Betancourt, R.Betancourt, Rafael >> | 32 | 2007 | R | 76 | 86 | 0 | 7 | 3 | 3.20 | .266 | 1.08 | 7.6 | 2.1 | 7.2 | 126.2 | 107 | 50 | 45 | 20 | 30 | 101 | 0 | 11 | 4 | 0 | 0 | 1 | 0 | 4.20 |
| RP | Broxton, J.Broxton, Jonathan >> | 25 | 2009 | R | 62 | 69 | 0 | 4 | 3 | 4.20 | .318 | 1.40 | 8.2 | 4.4 | 8.2 | 83.2 | 76 | 41 | 39 | 12 | 41 | 76 | 0 | 11 | 2 | 0 | 0 | 0 | 4 | 4.53 |
| RP | Wuertz, M.Wuertz, Michael >> | 31 | 2009 | R | 54 | 55 | 0 | 3 | 3 | 5.29 | .326 | 1.44 | 8.0 | 5.1 | 7.9 | 64.2 | 57 | 40 | 38 | 10 | 36 | 56 | 0 | 7 | 2 | 0 | 0 | 1 | 3 | 5.02 |