| SP | Koufax, S.Koufax, Sandy >> | 30 | 1965 | L | 97 | 23 | 23 | 10 | 9 | 4.06 | .303 | 1.29 | 8.1 | 3.5 | 8.0 | 168.2 | 152 | 84 | 76 | 18 | 65 | 149 | 4 | 0 | 0 | 1 | 13 | 3 | 4 | 3.83 |
| SP | Brown, M.Brown, Mordecai >> | 32 | 1908 | R | 85 | 22 | 22 | 7 | 11 | 4.63 | .316 | 1.35 | 9.8 | 2.4 | 4.5 | 145.2 | 158 | 85 | 75 | 19 | 39 | 72 | 3 | 0 | 0 | 0 | 11 | 5 | 2 | 4.62 |
| SP | Clemens, R.Clemens, Roger # >> | 24 | 1986 | R | 69 | 22 | 22 | 7 | 10 | 5.66 | .333 | 1.46 | 10.3 | 2.9 | 5.4 | 152.2 | 174 | 101 | 96 | 24 | 49 | 91 | 6 | 0 | 0 | 1 | 4 | 6 | 1 | 4.94 |
| SP | Caldwell, R.Caldwell, Ray >> | 26 | 1914 | R | 64 | 22 | 22 | 7 | 8 | 6.67 | .368 | 1.72 | 11.8 | 3.7 | 3.9 | 114.2 | 150 | 98 | 85 | 21 | 47 | 50 | 0 | 0 | 0 | 0 | 7 | 3 | 0 | 5.83 |
| SP | Harden, R.Harden, Rich >> | 27 | 2008 | R | 60 | 21 | 21 | 7 | 5 | 4.60 | .331 | 1.48 | 8.1 | 5.3 | 8.8 | 101.2 | 91 | 52 | 52 | 16 | 59 | 99 | 0 | 0 | 0 | 0 | 3 | 1 | 1 | 4.88 |
| RP | Jansen, K.Jansen, Kenley >> | 28 | 2016 | R | 97 | 56 | 0 | 6 | 1 | 2.11 | .248 | 0.99 | 7.2 | 1.8 | 9.1 | 76.2 | 61 | 25 | 18 | 8 | 15 | 77 | 0 | 3 | 1 | 0 | 0 | 0 | 0 | 2.93 |
| RP | Rivera, M.Rivera, Mariano # >> | 39 | 2008 | R | 85 | 46 | 0 | 1 | 3 | 5.06 | .328 | 1.44 | 10.9 | 2.2 | 8.5 | 53.1 | 64 | 35 | 30 | 7 | 13 | 50 | 0 | 7 | 3 | 0 | 0 | 1 | 1 | 3.62 |
| RP | Holland, G.Holland, Greg >> | 27 | 2013 | R | 71 | 38 | 0 | 1 | 3 | 5.33 | .340 | 1.51 | 10.6 | 3.1 | 10.4 | 52.1 | 61 | 36 | 31 | 10 | 18 | 60 | 0 | 2 | 4 | 0 | 0 | 2 | 3 | 4.35 |
| SP | Camnitz, H.Camnitz, Howie >> | 28 | 1909 | R | 56 | 4 | 0 | 0 | 0 | 0.00 | .313 | 1.36 | 9.0 | 6.0 | 0.0 | 3.2 | 3 | 0 | 0 | 0 | 2 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 5.00 |