| SP | deGrom, J.deGrom, Jacob >> | 33 | 2021 | R | 100 | 32 | 32 | 15 | 7 | 3.28 | .264 | 1.03 | 7.0 | 2.2 | 10.3 | 203.0 | 159 | 80 | 74 | 32 | 50 | 232 | 1 | 0 | 0 | 0 | 21 | 9 | 0 | 3.64 |
| SP | Richard, J.Richard, J.R. † >> | 30 | 1980 | R | 90 | 31 | 31 | 14 | 10 | 3.89 | .313 | 1.34 | 8.4 | 3.7 | 8.1 | 196.2 | 183 | 93 | 85 | 19 | 81 | 176 | 1 | 0 | 0 | 1 | 19 | 5 | 4 | 3.78 |
| SP | Adams, B.Adams, Babe # >> | 27 | 1909 | R | 86 | 31 | 31 | 8 | 10 | 5.58 | .340 | 1.52 | 11.0 | 2.7 | 4.9 | 156.1 | 191 | 103 | 97 | 23 | 47 | 85 | 0 | 0 | 0 | 0 | 7 | 4 | 4 | 4.81 |
| RP | Eckersley, D.Eckersley, Dennis >> | 36 | 1990 | R | 88 | 76 | 0 | 5 | 4 | 4.01 | .314 | 1.34 | 10.4 | 1.7 | 8.9 | 89.2 | 103 | 41 | 40 | 7 | 17 | 88 | 0 | 1 | 1 | 0 | 0 | 3 | 0 | 2.72 |
| RP | Benitez, A.Benitez, Armando >> | 32 | 2004 | R | 81 | 58 | 0 | 6 | 1 | 3.27 | .293 | 1.23 | 7.2 | 3.8 | 7.2 | 66.0 | 53 | 25 | 24 | 7 | 28 | 53 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 4.09 |
| RP | Hochevar, L.Hochevar, Luke >> | 30 | 2013 | R | 77 | 41 | 0 | 3 | 0 | 3.89 | .318 | 1.40 | 9.9 | 2.8 | 8.5 | 39.1 | 43 | 19 | 17 | 4 | 12 | 37 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 3.36 |
| RP | Zimmerman, J.Zimmerman, Jeff >> | 27 | 1999 | R | 70 | 31 | 0 | 1 | 2 | 3.40 | .314 | 1.30 | 7.3 | 4.5 | 4.7 | 42.1 | 34 | 16 | 16 | 5 | 21 | 22 | 0 | 0 | 0 | 0 | 0 | 3 | 3 | 5.21 |