| SP | Kershaw, C.Kershaw, Clayton >> | 28 | 2016 | L | 99 | 33 | 33 | 13 | 15 | 3.87 | .290 | 1.21 | 8.7 | 2.3 | 8.3 | 248.2 | 240 | 119 | 107 | 29 | 62 | 229 | 3 | 0 | 0 | 1 | 19 | 3 | 9 | 3.46 |
| SP | Brown, M.Brown, Mordecai >> | 32 | 1908 | R | 85 | 32 | 32 | 10 | 11 | 4.37 | .303 | 1.28 | 8.7 | 2.8 | 4.2 | 237.0 | 229 | 123 | 115 | 25 | 75 | 111 | 5 | 0 | 0 | 0 | 17 | 5 | 6 | 4.45 |
| SP | Bender, C.Bender, Chief # >> | 26 | 1910 | R | 71 | 31 | 31 | 8 | 16 | 6.13 | .348 | 1.56 | 11.3 | 2.7 | 5.0 | 215.2 | 271 | 157 | 147 | 34 | 65 | 120 | 7 | 0 | 0 | 0 | 7 | 9 | 11 | 4.97 |
| SP | Waddell, R.Waddell, Rube † >> | 29 | 1905 | L | 67 | 31 | 31 | 18 | 9 | 3.80 | .290 | 1.22 | 7.9 | 3.1 | 4.9 | 234.2 | 205 | 107 | 99 | 18 | 81 | 128 | 8 | 0 | 0 | 3 | 18 | 2 | 7 | 3.97 |
| RP | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 85 | 68 | 0 | 2 | 3 | 2.96 | .290 | 1.18 | 8.3 | 2.4 | 7.9 | 76.0 | 70 | 27 | 25 | 5 | 20 | 67 | 0 | 11 | 1 | 0 | 0 | 3 | 0 | 3.00 |
| RP | Harvey, B.Harvey, Bryan >> | 28 | 1991 | R | 66 | 33 | 0 | 2 | 3 | 5.66 | .344 | 1.55 | 11.6 | 2.4 | 7.9 | 41.1 | 53 | 27 | 26 | 8 | 11 | 36 | 0 | 1 | 0 | 0 | 0 | 1 | 3 | 4.66 |
| RP | Foulke, K.Foulke, Keith >> | 27 | 1999 | R | 59 | 32 | 0 | 1 | 2 | 4.72 | .344 | 1.54 | 9.5 | 4.5 | 8.7 | 34.1 | 36 | 19 | 18 | 6 | 17 | 33 | 0 | 1 | 2 | 0 | 0 | 1 | 0 | 4.94 |
| SP | Drysdale, D.Drysdale, Don >> | 28 | 1964 | R | 59 | 3 | 0 | 1 | 0 | 0.00 | .417 | 2.14 | 13.5 | 9.0 | 4.5 | 2.1 | 3 | 0 | 0 | 0 | 2 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.00 |
| SP | Overall, O.Overall, Orval >> | 28 | 1909 | R | 57 | 13 | 0 | 2 | 2 | 6.29 | .348 | 1.60 | 10.5 | 4.1 | 5.3 | 24.1 | 28 | 17 | 17 | 5 | 11 | 14 | 0 | 1 | 2 | 0 | 0 | 0 | 1 | 5.92 |