| SP | Greinke, Z.Greinke, Zack >> | 32 | 2015 | R | 94 | 22 | 22 | 10 | 6 | 3.64 | .278 | 1.13 | 8.3 | 1.9 | 4.5 | 160.2 | 148 | 65 | 65 | 17 | 33 | 80 | 2 | 0 | 0 | 0 | 13 | 5 | 2 | 4.09 |
| SP | Scherzer, M.Scherzer, Max † >> | 33 | 2017 | R | 95 | 23 | 23 | 14 | 5 | 2.77 | .279 | 1.14 | 6.6 | 3.7 | 8.9 | 159.1 | 116 | 54 | 49 | 15 | 65 | 158 | 1 | 0 | 0 | 0 | 16 | 4 | 3 | 3.54 |
| SP | Schmidt, J.Schmidt, Jason # >> | 30 | 2003 | R | 67 | 22 | 22 | 7 | 8 | 5.14 | .335 | 1.48 | 9.5 | 3.9 | 7.3 | 117.1 | 123 | 71 | 67 | 9 | 51 | 95 | 0 | 0 | 0 | 0 | 9 | 3 | 2 | 3.76 |
| SP | Hendrix, C.Hendrix, Claude # >> | 25 | 1914 | R | 69 | 22 | 22 | 5 | 5 | 4.35 | .323 | 1.40 | 9.2 | 3.4 | 5.4 | 128.1 | 131 | 64 | 62 | 8 | 49 | 77 | 1 | 0 | 0 | 0 | 13 | 4 | 1 | 3.85 |
| RP | Betancourt, R.Betancourt, Rafael # >> | 32 | 2007 | R | 76 | 59 | 0 | 3 | 3 | 4.62 | .321 | 1.41 | 10.2 | 2.4 | 6.7 | 74.0 | 84 | 38 | 38 | 10 | 20 | 55 | 0 | 2 | 1 | 0 | 0 | 1 | 0 | 4.12 |
| RP | Soria, J.Soria, Joakim >> | 24 | 2008 | R | 68 | 43 | 0 | 6 | 3 | 3.27 | .292 | 1.20 | 7.0 | 3.8 | 5.2 | 55.0 | 43 | 21 | 20 | 4 | 23 | 32 | 0 | 0 | 0 | 0 | 0 | 2 | 2 | 4.15 |
| RP | Treinen, B.Treinen, Blake >> | 30 | 2018 | R | 79 | 33 | 0 | 5 | 2 | 2.38 | .294 | 1.18 | 7.2 | 3.5 | 7.2 | 41.2 | 33 | 15 | 11 | 3 | 16 | 33 | 0 | 0 | 0 | 0 | 0 | 3 | 3 | 3.73 |
| CL | Hader, J.Hader, Josh † >> | 24 | 2018 | L | 93 | 43 | 0 | 2 | 2 | 1.00 | .250 | 1.00 | 6.0 | 3.0 | 10.8 | 45.0 | 30 | 9 | 5 | 4 | 15 | 54 | 0 | 24 | 2 | 0 | 0 | 0 | 0 | 2.76 |
| SP | Ellsworth, D.Ellsworth, Dick >> | 23 | 1963 | L | 26 | 4 | 0 | 0 | 1 | 1.23 | .267 | 1.09 | 5.1 | 5.1 | 9.0 | 7.1 | 4 | 3 | 1 | 1 | 4 | 7 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 4.57 |
| SP | McGinnity, J.McGinnity, Joe >> | 33 | 1904 | R | 50 | 2 | 0 | 1 | 0 | 0.00 | .100 | 0.33 | 3.0 | 0.0 | 0.0 | 6.0 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.00 |