| SP | Kluber, C.Kluber, Corey >> | 31 | 2017 | R | 90 | 11 | 11 | 2 | 2 | 5.46 | .322 | 1.39 | 8.4 | 4.1 | 10.0 | 61.0 | 57 | 39 | 37 | 10 | 28 | 68 | 0 | 0 | 0 | 0 | 5 | 2 | 1 | 4.38 |
| SP | Maddux, G.Maddux, Greg # >> | 29 | 1995 | R | 89 | 31 | 31 | 9 | 14 | 4.74 | .308 | 1.33 | 9.7 | 2.3 | 5.2 | 197.2 | 212 | 113 | 104 | 28 | 51 | 113 | 6 | 0 | 0 | 3 | 12 | 1 | 2 | 4.49 |
| SP | Alexander, P.Alexander, Pete >> | 28 | 1915 | R | 88 | 9 | 9 | 4 | 3 | 5.63 | .315 | 1.33 | 9.3 | 2.7 | 5.7 | 54.1 | 56 | 36 | 34 | 12 | 16 | 34 | 1 | 0 | 0 | 1 | 3 | 3 | 1 | 5.69 |
| SP | McLain, D.McLain, Denny >> | 24 | 1968 | R | 79 | 32 | 32 | 10 | 9 | 5.19 | .326 | 1.43 | 9.2 | 3.6 | 5.3 | 183.2 | 188 | 109 | 106 | 32 | 74 | 108 | 8 | 0 | 0 | 3 | 12 | 5 | 4 | 5.39 |
| RP | Doolittle, S.Doolittle, Sean # >> | 31 | 2018 | L | 99 | 66 | 0 | 6 | 8 | 5.03 | .332 | 1.47 | 10.5 | 2.7 | 8.7 | 59.0 | 69 | 35 | 33 | 11 | 18 | 57 | 0 | 20 | 9 | 0 | 0 | 1 | 4 | 4.46 |
| RP | Benoit, J.Benoit, Joaquin >> | 33 | 2010 | R | 95 | 89 | 0 | 8 | 4 | 4.88 | .309 | 1.32 | 8.1 | 3.9 | 8.3 | 99.2 | 89 | 59 | 54 | 12 | 43 | 91 | 0 | 3 | 1 | 0 | 0 | 2 | 1 | 4.10 |
| RP | Miller, A.Miller, Andrew >> | 29 | 2014 | L | 88 | 46 | 0 | 1 | 2 | 2.45 | .270 | 1.11 | 6.3 | 3.8 | 10.1 | 47.2 | 33 | 13 | 13 | 4 | 20 | 53 | 0 | 3 | 2 | 0 | 0 | 0 | 0 | 3.13 |
| RP | Clippard, T.Clippard, Tyler >> | 26 | 2011 | R | 79 | 48 | 0 | 1 | 3 | 6.10 | .357 | 1.62 | 9.9 | 4.9 | 7.9 | 48.2 | 53 | 33 | 33 | 9 | 26 | 42 | 0 | 5 | 6 | 0 | 0 | 2 | 0 | 5.44 |
| RP | Zimmerman, J.Zimmerman, Jeff >> | 27 | 1999 | R | 70 | 36 | 0 | 2 | 1 | 3.10 | .290 | 1.18 | 6.4 | 4.3 | 5.5 | 52.1 | 37 | 19 | 18 | 6 | 25 | 32 | 0 | 0 | 0 | 0 | 0 | 2 | 1 | 4.83 |
| SP | Pfiester, J.Pfiester, Jack >> | 28 | 1906 | L | 74 | 27 | 25 | 8 | 11 | 5.20 | .344 | 1.54 | 10.5 | 3.4 | 4.5 | 147.0 | 171 | 94 | 85 | 27 | 56 | 74 | 3 | 0 | 0 | 0 | 10 | 4 | 7 | 5.61 |