| SP | Verlander, J.Verlander, Justin >> | 36 | 2019 | R | 99 | 23 | 23 | 9 | 9 | 4.90 | .302 | 1.25 | 9.1 | 2.2 | 8.3 | 132.1 | 133 | 78 | 72 | 20 | 32 | 121 | 0 | 0 | 0 | 0 | 12 | 7 | 2 | 4.02 |
| SP | Kluber, C.Kluber, Corey >> | 31 | 2017 | R | 89 | 22 | 22 | 8 | 7 | 4.58 | .305 | 1.30 | 8.5 | 3.3 | 7.9 | 143.1 | 135 | 74 | 73 | 17 | 52 | 125 | 1 | 0 | 0 | 0 | 13 | 2 | 3 | 3.93 |
| SP | Horlen, J.Horlen, Joe # >> | 27 | 1964 | R | 78 | 22 | 22 | 7 | 4 | 5.08 | .308 | 1.31 | 9.1 | 2.7 | 4.7 | 131.0 | 132 | 77 | 74 | 25 | 39 | 68 | 2 | 0 | 0 | 0 | 12 | 4 | 1 | 5.43 |
| SP | Waddell, R.Waddell, Rube † >> | 29 | 1905 | L | 67 | 24 | 22 | 12 | 5 | 3.65 | .298 | 1.24 | 7.7 | 3.4 | 5.1 | 158.0 | 136 | 68 | 64 | 13 | 60 | 89 | 1 | 0 | 0 | 1 | 14 | 5 | 5 | 4.18 |
| RP | Clippard, T.Clippard, Tyler >> | 26 | 2011 | R | 79 | 32 | 0 | 6 | 1 | 2.60 | .257 | 1.04 | 5.6 | 4.0 | 7.4 | 34.2 | 21 | 10 | 10 | 3 | 15 | 28 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 3.82 |
| RP | Pagan, E.Pagan, Emilio >> | 28 | 2019 | R | 77 | 19 | 0 | 0 | 0 | 2.55 | .275 | 1.14 | 9.0 | 1.5 | 9.4 | 24.2 | 24 | 7 | 7 | 2 | 4 | 25 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 2.50 |
| RP | Wilhelm, H.Wilhelm, Hoyt >> | 43 | 1965 | R | 68 | 22 | 0 | 1 | 1 | 6.03 | .377 | 1.79 | 11.3 | 4.9 | 5.8 | 31.1 | 39 | 21 | 21 | 7 | 17 | 20 | 0 | 0 | 0 | 0 | 0 | 1 | 3 | 6.39 |
| CL | Adams, M.Adams, Mike † >> | 31 | 2009 | R | 99 | 40 | 0 | 2 | 5 | 2.70 | .240 | 0.95 | 5.9 | 2.7 | 9.4 | 43.1 | 28 | 13 | 13 | 3 | 13 | 45 | 0 | 22 | 2 | 0 | 0 | 0 | 1 | 2.72 |