| SP | Tiant, L.Tiant, Luis # >> | 28 | 1968 | R | 97 | 32 | 32 | 9 | 15 | 5.14 | .332 | 1.47 | 10.2 | 3.0 | 7.3 | 206.2 | 234 | 142 | 118 | 30 | 69 | 167 | 3 | 0 | 0 | 1 | 12 | 5 | 5 | 4.35 |
| SP | Maddux, G.Maddux, Greg † >> | 29 | 1995 | R | 89 | 30 | 30 | 16 | 8 | 3.72 | .304 | 1.29 | 9.4 | 2.3 | 5.4 | 232.0 | 242 | 113 | 96 | 16 | 58 | 139 | 9 | 0 | 0 | 1 | 16 | 4 | 4 | 3.50 |
| SP | Johnson, R.Johnson, Randy >> | 41 | 2004 | L | 84 | 32 | 32 | 13 | 11 | 5.51 | .326 | 1.42 | 10.0 | 2.9 | 7.7 | 204.1 | 226 | 128 | 125 | 34 | 65 | 174 | 2 | 0 | 0 | 0 | 9 | 6 | 3 | 4.50 |
| SP | Fernandez, J.Fernandez, Jose >> | 21 | 2013 | R | 76 | 31 | 31 | 11 | 11 | 5.36 | .345 | 1.54 | 9.0 | 4.9 | 7.8 | 171.1 | 171 | 104 | 102 | 24 | 93 | 148 | 0 | 0 | 0 | 0 | 15 | 7 | 1 | 4.85 |
| SP | Hendrix, C.Hendrix, Claude >> | 25 | 1914 | R | 69 | 31 | 29 | 7 | 15 | 6.82 | .374 | 1.79 | 12.5 | 3.6 | 4.7 | 162.1 | 225 | 126 | 123 | 24 | 65 | 84 | 1 | 0 | 0 | 0 | 9 | 1 | 5 | 5.11 |
| RP | Feliz, N.Feliz, Neftali † >> | 21 | 2009 | R | 97 | 84 | 0 | 8 | 5 | 3.01 | .280 | 1.14 | 6.8 | 3.5 | 8.3 | 137.1 | 103 | 53 | 46 | 12 | 53 | 127 | 0 | 9 | 2 | 0 | 0 | 4 | 0 | 3.53 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 81 | 0 | 5 | 6 | 3.12 | .294 | 1.23 | 8.1 | 2.9 | 8.2 | 101.0 | 91 | 43 | 35 | 11 | 33 | 92 | 0 | 9 | 0 | 0 | 0 | 2 | 0 | 3.63 |
| RP | Soriano, R.Soriano, Rafael >> | 24 | 2003 | R | 84 | 63 | 0 | 5 | 2 | 4.71 | .325 | 1.39 | 9.0 | 3.6 | 9.8 | 80.1 | 80 | 42 | 42 | 9 | 32 | 87 | 0 | 12 | 1 | 0 | 0 | 4 | 0 | 3.64 |
| RP | Balfour, G.Balfour, Grant >> | 31 | 2008 | R | 75 | 42 | 0 | 3 | 2 | 3.67 | .297 | 1.27 | 6.1 | 5.3 | 9.0 | 49.0 | 33 | 25 | 20 | 7 | 29 | 49 | 0 | 7 | 1 | 0 | 0 | 0 | 2 | 4.63 |
| RP | Dotel, O.Dotel, Octavio >> | 29 | 2002 | R | 69 | 36 | 0 | 1 | 1 | 4.30 | .327 | 1.41 | 9.5 | 3.4 | 10.2 | 37.2 | 39 | 18 | 18 | 4 | 14 | 42 | 0 | 4 | 0 | 0 | 0 | 2 | 0 | 3.43 |