| SP | Scherzer, M.Scherzer, Max † >> | 33 | 2017 | R | 100 | 24 | 24 | 15 | 7 | 3.40 | .286 | 1.18 | 6.6 | 4.1 | 10.1 | 159.0 | 116 | 63 | 60 | 13 | 72 | 179 | 3 | 0 | 0 | 1 | 16 | 3 | 3 | 3.23 |
| SP | Strasburg, S.Strasburg, Stephen >> | 28 | 2017 | R | 84 | 23 | 23 | 9 | 11 | 5.25 | .321 | 1.40 | 9.5 | 3.2 | 10.9 | 130.1 | 137 | 76 | 76 | 21 | 46 | 158 | 0 | 0 | 0 | 0 | 9 | 2 | 1 | 3.78 |
| SP | Gullickson, B.Gullickson, Bill >> | 22 | 1981 | R | 50 | 23 | 23 | 10 | 10 | 4.14 | .326 | 1.43 | 9.6 | 3.2 | 5.9 | 156.1 | 167 | 84 | 72 | 16 | 56 | 102 | 1 | 0 | 0 | 0 | 12 | 4 | 3 | 4.18 |
| SU | Albers, M.Albers, Matt >> | 34 | 2017 | R | 95 | 52 | 0 | 0 | 0 | 2.98 | .318 | 1.38 | 7.5 | 5.0 | 9.2 | 54.1 | 45 | 19 | 18 | 5 | 30 | 55 | 0 | 3 | 2 | 0 | 0 | 1 | 0 | 3.89 |
| RP | Reardon, J.Reardon, Jeff >> | 26 | 1981 | R | 78 | 56 | 0 | 1 | 2 | 3.58 | .292 | 1.21 | 7.5 | 3.5 | 6.3 | 70.1 | 58 | 33 | 28 | 5 | 27 | 49 | 0 | 2 | 0 | 0 | 0 | 2 | 0 | 3.77 |
| RP | Perez, P.Perez, Pascual >> | 30 | 1987 | R | 74 | 23 | 0 | 2 | 0 | 3.58 | .303 | 1.30 | 7.3 | 4.7 | 6.7 | 27.2 | 22 | 14 | 11 | 2 | 14 | 20 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.04 |
| RP | Madson, R.Madson, Ryan >> | 37 | 2017 | R | 96 | 51 | 0 | 6 | 2 | 3.08 | .291 | 1.22 | 7.4 | 3.6 | 9.7 | 52.2 | 43 | 18 | 18 | 8 | 21 | 56 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 4.12 |
| RP | Doolittle, S.Doolittle, Sean >> | 30 | 2017 | L | 93 | 31 | 0 | 1 | 0 | 6.49 | .331 | 1.48 | 11.1 | 2.4 | 14.9 | 26.1 | 32 | 19 | 19 | 3 | 7 | 43 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 2.00 |