| SP | Sanchez, A.Sanchez, Anibal >> | 27 | 2006 | R | 95 | 26 | 26 | 9 | 8 | 3.58 | .283 | 1.17 | 7.8 | 2.7 | 6.5 | 173.1 | 150 | 74 | 69 | 16 | 52 | 124 | 1 | 0 | 0 | 0 | 16 | 3 | 1 | 3.72 |
| SP | Zambrano, C.Zambrano, Carlos # >> | 30 | 2005 | R | 95 | 26 | 26 | 4 | 14 | 4.60 | .305 | 1.30 | 8.5 | 3.2 | 7.0 | 162.1 | 153 | 86 | 83 | 29 | 58 | 126 | 3 | 0 | 0 | 1 | 14 | 3 | 5 | 4.90 |
| SP | Karstens, J.Karstens, Jeff # >> | 29 | 2006 | R | 81 | 24 | 24 | 10 | 8 | 4.61 | .314 | 1.36 | 9.8 | 2.5 | 4.8 | 142.2 | 155 | 77 | 73 | 20 | 39 | 76 | 0 | 0 | 0 | 0 | 11 | 2 | 4 | 4.63 |
| SU | Thompson, B.Thompson, Brad >> | 29 | 2005 | R | 89 | 38 | 0 | 1 | 3 | 3.13 | .233 | 0.91 | 6.8 | 1.5 | 6.3 | 37.1 | 28 | 14 | 13 | 4 | 6 | 26 | 0 | 4 | 6 | 0 | 0 | 0 | 0 | 3.49 |
| RP | Rowland-Smith, R.Rowland-Smith, Ryan >> | 28 | 2007 | L | 92 | 64 | 0 | 2 | 1 | 2.92 | .269 | 1.07 | 7.1 | 2.7 | 9.1 | 61.2 | 48 | 20 | 20 | 7 | 18 | 62 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 3.44 |
| RP | Wainwright, A.Wainwright, Adam >> | 30 | 2006 | R | 83 | 56 | 0 | 3 | 4 | 1.79 | .262 | 1.05 | 7.1 | 2.4 | 9.3 | 70.1 | 55 | 16 | 14 | 3 | 19 | 72 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 2.36 |
| RP | Hawksworth, B.Hawksworth, Blake >> | 28 | 2009 | R | 82 | 22 | 0 | 1 | 0 | 2.17 | .273 | 1.10 | 6.6 | 3.4 | 6.6 | 37.1 | 27 | 12 | 9 | 4 | 14 | 27 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 4.16 |
| RP | Salas, F.Salas, Fernando >> | 26 | 2011 | R | 86 | 13 | 0 | 2 | 2 | 2.08 | .264 | 1.08 | 8.3 | 1.4 | 9.0 | 13.0 | 12 | 3 | 3 | 1 | 2 | 13 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2.46 |
| RP | McClellan, K.McClellan, Kyle >> | 27 | 2010 | R | 82 | 10 | 0 | 1 | 0 | 4.32 | .375 | 1.80 | 13.5 | 3.4 | 12.4 | 8.1 | 12 | 4 | 4 | 2 | 3 | 11 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.63 |
| SP | Hellickson, J.Hellickson, Jeremy >> | 24 | 2010 | R | 84 | 21 | 0 | 2 | 2 | 4.71 | .293 | 1.21 | 8.7 | 2.3 | 5.6 | 80.1 | 77 | 49 | 42 | 10 | 20 | 50 | 0 | 0 | 0 | 0 | 0 | 3 | 2 | 4.24 |