| SP | Sanchez, A.Sanchez, Anibal # >> | 28 | 2006 | R | 97 | 23 | 23 | 6 | 11 | 5.30 | .308 | 1.32 | 9.8 | 2.1 | 5.5 | 127.1 | 138 | 77 | 75 | 22 | 30 | 78 | 0 | 0 | 0 | 0 | 9 | 2 | 2 | 4.78 |
| SP | Hellickson, J.Hellickson, Jeremy # >> | 25 | 2010 | R | 91 | 23 | 23 | 5 | 6 | 4.11 | .295 | 1.20 | 8.7 | 2.2 | 5.7 | 103.0 | 99 | 49 | 47 | 16 | 25 | 65 | 0 | 0 | 0 | 0 | 1 | 5 | 3 | 4.63 |
| SP | Zambrano, C.Zambrano, Carlos # >> | 31 | 2005 | R | 93 | 23 | 23 | 6 | 12 | 5.97 | .317 | 1.37 | 9.3 | 3.1 | 8.1 | 126.2 | 130 | 87 | 84 | 20 | 44 | 113 | 2 | 0 | 0 | 0 | 8 | 2 | 0 | 4.37 |
| SP | Jimenez, U.Jimenez, Ubaldo >> | 28 | 2007 | R | 92 | 22 | 22 | 6 | 13 | 5.33 | .332 | 1.43 | 9.3 | 3.6 | 6.7 | 123.1 | 127 | 77 | 73 | 23 | 49 | 91 | 0 | 0 | 0 | 0 | 8 | 8 | 3 | 5.34 |
| CL | Salas, F.Salas, Fernando >> | 27 | 2011 | R | 93 | 42 | 0 | 4 | 6 | 2.33 | .291 | 1.21 | 7.2 | 3.7 | 9.2 | 46.1 | 37 | 18 | 12 | 2 | 19 | 47 | 0 | 28 | 4 | 0 | 0 | 1 | 1 | 2.83 |
| RP | Thompson, B.Thompson, Brad >> | 30 | 2005 | R | 88 | 56 | 0 | 5 | 2 | 3.12 | .252 | 0.99 | 6.2 | 2.7 | 6.9 | 78.0 | 54 | 30 | 27 | 11 | 23 | 60 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 4.26 |
| RP | Rowland-Smith, R.Rowland-Smith, Ryan >> | 29 | 2007 | L | 89 | 44 | 0 | 0 | 0 | 2.19 | .275 | 1.07 | 6.8 | 2.9 | 8.6 | 49.1 | 37 | 14 | 12 | 5 | 16 | 47 | 0 | 1 | 2 | 0 | 0 | 3 | 0 | 3.57 |
| RP | McClellan, K.McClellan, Kyle >> | 28 | 2010 | R | 85 | 31 | 0 | 2 | 1 | 2.76 | .246 | 0.95 | 6.8 | 2.0 | 6.5 | 32.2 | 24 | 10 | 10 | 2 | 7 | 23 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 3.13 |
| RP | Wainwright, A.Wainwright, Adam >> | 31 | 2006 | R | 82 | 19 | 0 | 3 | 0 | 2.54 | .267 | 1.06 | 6.4 | 3.2 | 9.3 | 28.1 | 20 | 8 | 8 | 2 | 10 | 29 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 3.04 |
| RP | Hawksworth, B.Hawksworth, Blake >> | 29 | 2009 | R | 80 | 19 | 0 | 1 | 0 | 1.46 | .204 | 0.73 | 6.0 | 0.8 | 5.3 | 24.2 | 16 | 4 | 4 | 1 | 2 | 14 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 2.75 |
| SP | Karstens, J.Karstens, Jeff >> | 30 | 2006 | R | 81 | 27 | 0 | 5 | 0 | 4.07 | .292 | 1.22 | 8.1 | 2.9 | 6.6 | 108.1 | 97 | 52 | 49 | 15 | 35 | 79 | 0 | 0 | 0 | 0 | 0 | 2 | 6 | 4.37 |