| SP | Darvish, Y.Darvish, Yu # >> | 29 | 2013 | R | 96 | 33 | 33 | 19 | 8 | 3.52 | .288 | 1.19 | 7.2 | 3.6 | 9.2 | 232.2 | 185 | 97 | 91 | 36 | 93 | 237 | 1 | 0 | 0 | 0 | 25 | 5 | 3 | 4.24 |
| SP | Morales, F.Morales, Franklin >> | 30 | 2007 | L | 95 | 33 | 32 | 16 | 7 | 3.98 | .288 | 1.19 | 8.5 | 2.2 | 7.1 | 219.1 | 207 | 105 | 97 | 34 | 54 | 172 | 3 | 0 | 0 | 2 | 17 | 5 | 0 | 4.26 |
| SP | Villanueva, C.Villanueva, Carlos >> | 33 | 2006 | R | 93 | 31 | 31 | 16 | 11 | 4.09 | .291 | 1.21 | 8.3 | 2.6 | 6.1 | 202.2 | 187 | 95 | 92 | 38 | 58 | 137 | 1 | 0 | 0 | 0 | 19 | 5 | 0 | 5.02 |
| SP | Salazar, D.Salazar, Danny >> | 26 | 2013 | R | 96 | 33 | 33 | 8 | 12 | 4.92 | .325 | 1.43 | 10.0 | 2.9 | 8.9 | 215.2 | 238 | 125 | 118 | 45 | 70 | 212 | 1 | 0 | 0 | 0 | 16 | 4 | 8 | 4.78 |
| RP | Pestano, V.Pestano, Vinnie >> | 31 | 2011 | R | 92 | 87 | 0 | 11 | 4 | 3.80 | .279 | 1.12 | 7.0 | 3.2 | 9.2 | 111.1 | 86 | 49 | 47 | 18 | 39 | 113 | 0 | 3 | 1 | 0 | 0 | 4 | 0 | 4.23 |
| RP | Broxton, J.Broxton, Jonathan >> | 32 | 2006 | R | 92 | 36 | 0 | 3 | 1 | 4.21 | .299 | 1.28 | 8.8 | 2.7 | 10.7 | 47.0 | 46 | 22 | 22 | 7 | 14 | 56 | 0 | 1 | 0 | 0 | 0 | 0 | 4 | 3.45 |
| RP | Devenski, C.Devenski, Chris >> | 25 | 2016 | R | 82 | 36 | 0 | 1 | 4 | 3.57 | .277 | 1.13 | 7.8 | 2.4 | 8.0 | 53.0 | 46 | 22 | 21 | 4 | 14 | 47 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 3.06 |
| CL | Manship, J.Manship, Jeff >> | 31 | 2015 | R | 94 | 70 | 0 | 2 | 10 | 3.00 | .299 | 1.22 | 6.9 | 4.1 | 6.4 | 72.0 | 55 | 28 | 24 | 7 | 33 | 51 | 0 | 43 | 7 | 0 | 0 | 4 | 0 | 4.39 |
| SP | Keuchel, D.Keuchel, Dallas >> | 28 | 2015 | L | 89 | 8 | 8 | 3 | 4 | 5.96 | .327 | 1.41 | 10.8 | 2.0 | 8.8 | 45.1 | 54 | 30 | 30 | 10 | 10 | 44 | 2 | 0 | 0 | 0 | 3 | 2 | 1 | 4.73 |
| SP | Carrasco, C.Carrasco, Carlos # >> | 29 | 2014 | R | 96 | 26 | 25 | 2 | 7 | 5.44 | .311 | 1.34 | 9.3 | 2.8 | 8.9 | 91.0 | 94 | 58 | 55 | 15 | 28 | 90 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 4.12 |