| SP | Nolasco, R.Nolasco, Ricky # >> | 29 | 2008 | R | 86 | 16 | 16 | 3 | 9 | 4.32 | .316 | 1.38 | 10.6 | 1.8 | 6.8 | 98.0 | 115 | 56 | 47 | 15 | 20 | 74 | 0 | 0 | 0 | 0 | 8 | 1 | 1 | 4.12 |
| SP | Verlander, J.Verlander, Justin # >> | 28 | 2007 | R | 86 | 27 | 27 | 10 | 11 | 5.02 | .310 | 1.33 | 9.1 | 2.9 | 5.5 | 166.2 | 167 | 96 | 93 | 34 | 54 | 102 | 2 | 0 | 0 | 0 | 10 | 4 | 7 | 5.48 |
| SP | Gorzelanny, T.Gorzelanny, Tom # >> | 29 | 2006 | L | 85 | 27 | 27 | 4 | 12 | 5.36 | .330 | 1.44 | 8.9 | 4.1 | 6.1 | 147.2 | 146 | 97 | 88 | 23 | 67 | 99 | 1 | 0 | 0 | 0 | 12 | 5 | 7 | 5.16 |
| SP | Lowry, N.Lowry, Noah # >> | 31 | 2004 | L | 84 | 28 | 27 | 4 | 13 | 5.00 | .314 | 1.34 | 9.2 | 2.9 | 6.4 | 147.2 | 151 | 82 | 82 | 27 | 47 | 104 | 1 | 1 | 0 | 0 | 12 | 5 | 1 | 5.03 |
| SP | Millwood, K.Millwood, Kevin >> | 37 | 1999 | R | 74 | 26 | 26 | 6 | 10 | 3.83 | .284 | 1.16 | 7.9 | 2.5 | 8.1 | 167.0 | 146 | 72 | 71 | 21 | 47 | 150 | 2 | 0 | 0 | 2 | 15 | 6 | 5 | 3.79 |
| SU | Valverde, J.Valverde, Jose # >> | 32 | 2003 | R | 100 | 72 | 0 | 6 | 4 | 4.13 | .260 | 1.04 | 6.8 | 2.6 | 9.3 | 96.0 | 72 | 45 | 44 | 9 | 28 | 99 | 0 | 0 | 6 | 0 | 0 | 1 | 1 | 3.06 |
| RP | Petit, Y.Petit, Yusmeiro >> | 27 | 2008 | R | 89 | 46 | 0 | 7 | 3 | 3.30 | .310 | 1.33 | 8.6 | 3.5 | 6.2 | 103.2 | 98 | 41 | 38 | 11 | 40 | 71 | 0 | 1 | 0 | 0 | 0 | 2 | 5 | 4.23 |
| CL | Alburquerque, A.Alburquerque, Al >> | 25 | 2011 | R | 78 | 51 | 0 | 4 | 0 | 2.10 | .297 | 1.23 | 5.8 | 5.3 | 10.2 | 51.1 | 33 | 12 | 12 | 2 | 30 | 58 | 0 | 18 | 3 | 0 | 0 | 2 | 3 | 3.12 |
| RP | Ramirez, R.Ramirez, Ramon >> | 30 | 2006 | R | 88 | 63 | 0 | 5 | 4 | 4.36 | .316 | 1.39 | 10.1 | 2.4 | 7.8 | 74.1 | 83 | 36 | 36 | 8 | 20 | 64 | 0 | 2 | 1 | 0 | 0 | 0 | 4 | 3.49 |
| RP | Walden, J.Walden, Jordan >> | 23 | 2011 | R | 58 | 19 | 0 | 0 | 2 | 2.82 | .330 | 1.48 | 7.4 | 6.1 | 7.8 | 22.1 | 18 | 14 | 7 | 2 | 15 | 19 | 0 | 4 | 1 | 0 | 0 | 0 | 0 | 4.50 |