| SP | Hudson, D.Hudson, Daniel >> | 26 | 2010 | R | 100 | 12 | 12 | 9 | 2 | 3.27 | .263 | 1.06 | 7.9 | 1.6 | 7.8 | 88.0 | 77 | 32 | 32 | 13 | 16 | 76 | 5 | 0 | 0 | 2 | 7 | 1 | 1 | 3.77 |
| SP | McCarthy, B.McCarthy, Brandon >> | 30 | 2005 | R | 94 | 11 | 11 | 5 | 4 | 3.75 | .286 | 1.19 | 8.5 | 2.3 | 6.2 | 84.0 | 79 | 38 | 35 | 11 | 21 | 58 | 6 | 0 | 0 | 0 | 7 | 1 | 0 | 4.11 |
| SP | Outman, J.Outman, Josh # >> | 29 | 2009 | L | 94 | 11 | 11 | 2 | 7 | 5.09 | .286 | 1.20 | 8.4 | 2.6 | 6.2 | 70.2 | 65 | 41 | 40 | 15 | 20 | 48 | 0 | 0 | 0 | 0 | 6 | 0 | 1 | 5.27 |
| SP | Buehrle, M.Buehrle, Mark >> | 34 | 2001 | L | 89 | 11 | 11 | 2 | 7 | 5.56 | .332 | 1.49 | 11.1 | 2.5 | 5.0 | 69.2 | 85 | 44 | 43 | 9 | 19 | 38 | 5 | 0 | 0 | 0 | 4 | 0 | 1 | 4.42 |
| SP | Davis, W.Davis, Wade # >> | 27 | 2009 | R | 89 | 11 | 11 | 1 | 5 | 4.48 | .297 | 1.24 | 8.1 | 3.1 | 8.4 | 70.1 | 63 | 37 | 35 | 8 | 24 | 65 | 1 | 0 | 0 | 0 | 6 | 2 | 2 | 3.74 |
| RP | Cordero, C.Cordero, Chad >> | 31 | 2004 | R | 96 | 15 | 0 | 3 | 1 | 2.88 | .250 | 1.00 | 7.2 | 1.8 | 8.3 | 25.0 | 20 | 8 | 8 | 3 | 5 | 23 | 0 | 1 | 2 | 0 | 0 | 0 | 1 | 3.32 |
| RP | Holland, G.Holland, Greg >> | 27 | 2011 | R | 96 | 8 | 0 | 0 | 0 | 1.64 | .195 | 0.73 | 6.5 | 0.0 | 11.5 | 11.0 | 8 | 2 | 2 | 2 | 0 | 14 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 2.82 |
| RP | Rodriguez, E.Rodriguez, Eddy >> | 32 | 2004 | R | 90 | 5 | 0 | 0 | 1 | 3.52 | .207 | 0.78 | 3.9 | 3.9 | 6.4 | 7.2 | 3 | 3 | 3 | 1 | 3 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.71 |