| SP | Liriano, F.Liriano, Francisco >> | 28 | 2006 | L | 100 | 27 | 27 | 12 | 6 | 3.02 | .252 | 0.98 | 7.3 | 1.6 | 8.1 | 175.2 | 142 | 60 | 59 | 14 | 31 | 157 | 0 | 0 | 0 | 0 | 19 | 5 | 9 | 2.86 |
| SP | Santana, J.Santana, Johan >> | 32 | 2004 | L | 99 | 27 | 27 | 11 | 9 | 3.61 | .270 | 1.07 | 7.2 | 2.4 | 9.4 | 199.1 | 160 | 80 | 80 | 22 | 53 | 208 | 7 | 0 | 0 | 2 | 15 | 8 | 4 | 3.27 |
| SP | Olsen, S.Olsen, Scott # >> | 27 | 2006 | L | 91 | 27 | 27 | 15 | 10 | 4.58 | .311 | 1.32 | 9.0 | 2.9 | 7.9 | 194.2 | 193 | 101 | 99 | 32 | 63 | 170 | 1 | 0 | 0 | 0 | 15 | 7 | 7 | 4.47 |
| SP | Worley, V.Worley, Vance # >> | 23 | 2011 | R | 63 | 27 | 27 | 5 | 9 | 6.38 | .358 | 1.65 | 10.4 | 4.4 | 7.3 | 134.0 | 155 | 98 | 95 | 28 | 66 | 108 | 0 | 0 | 0 | 0 | 4 | 3 | 1 | 5.65 |
| RP | Rodriguez, F.Rodriguez, Francisco >> | 29 | 2003 | R | 100 | 72 | 0 | 7 | 4 | 3.00 | .268 | 1.09 | 7.2 | 2.6 | 9.8 | 123.0 | 99 | 44 | 41 | 13 | 35 | 134 | 0 | 3 | 2 | 0 | 0 | 1 | 1 | 3.07 |
| RP | Littleton, W.Littleton, Wes >> | 29 | 2006 | R | 97 | 55 | 0 | 8 | 5 | 3.42 | .283 | 1.18 | 6.7 | 3.9 | 5.6 | 71.0 | 53 | 28 | 27 | 3 | 31 | 44 | 0 | 2 | 6 | 0 | 0 | 0 | 0 | 3.62 |
| RP | Francisco, F.Francisco, Frank # >> | 32 | 2004 | R | 92 | 36 | 0 | 3 | 1 | 4.54 | .285 | 1.19 | 8.3 | 2.7 | 9.5 | 37.2 | 34 | 19 | 19 | 4 | 11 | 39 | 0 | 3 | 2 | 0 | 0 | 0 | 1 | 3.19 |
| RP | Buchholz, T.Buchholz, Taylor >> | 30 | 2008 | R | 90 | 16 | 0 | 1 | 0 | 2.76 | .258 | 1.04 | 7.3 | 2.3 | 5.6 | 16.1 | 13 | 5 | 5 | 1 | 4 | 10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.31 |
| RP | Burgos, A.Burgos, Ambiorix >> | 27 | 2005 | R | 86 | 9 | 0 | 1 | 0 | 5.27 | .293 | 1.24 | 9.0 | 2.8 | 6.9 | 13.2 | 13 | 8 | 8 | 0 | 4 | 10 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 2.38 |