| SP | Bauer, T.Bauer, Trevor >> | 30 | 2021 | R | 97 | 36 | 36 | 22 | 5 | 2.21 | .265 | 1.06 | 5.8 | 3.7 | 11.5 | 253.0 | 164 | 69 | 62 | 21 | 103 | 322 | 2 | 0 | 0 | 1 | 27 | 7 | 4 | 2.84 |
| SP | Burnes, C.Burnes, Corbin >> | 26 | 2021 | R | 97 | 36 | 36 | 17 | 10 | 3.22 | .271 | 1.09 | 7.3 | 2.5 | 10.6 | 235.0 | 191 | 86 | 84 | 28 | 65 | 278 | 1 | 0 | 0 | 0 | 24 | 6 | 5 | 3.09 |
| SP | Musgrove, J.Musgrove, Joseph >> | 28 | 2021 | R | 89 | 35 | 35 | 15 | 12 | 4.43 | .317 | 1.31 | 8.8 | 3.1 | 9.1 | 205.1 | 200 | 102 | 101 | 20 | 70 | 208 | 1 | 0 | 0 | 1 | 16 | 16 | 0 | 3.50 |
| SP | Flaherty, J.Flaherty, Jack >> | 25 | 2021 | R | 93 | 31 | 31 | 10 | 10 | 3.82 | .303 | 1.30 | 7.5 | 4.2 | 9.2 | 155.1 | 130 | 66 | 66 | 17 | 72 | 158 | 0 | 0 | 0 | 0 | 6 | 1 | 6 | 3.80 |
| SP | Bieber, S.Bieber, Shane >> | 26 | 2021 | R | 74 | 28 | 28 | 9 | 9 | 5.10 | .348 | 1.57 | 9.9 | 4.2 | 11.4 | 164.0 | 180 | 98 | 93 | 19 | 77 | 207 | 0 | 0 | 0 | 0 | 10 | 6 | 5 | 3.50 |
| RP | Sadler, C.Sadler, Casey >> | 30 | 2021 | R | 97 | 40 | 0 | 4 | 2 | 2.85 | .268 | 1.10 | 5.9 | 4.1 | 9.3 | 53.2 | 35 | 17 | 17 | 5 | 24 | 55 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 3.51 |
| RP | Melancon, M.Melancon, Mark >> | 36 | 2021 | R | 57 | 70 | 0 | 6 | 2 | 2.81 | .298 | 1.25 | 6.4 | 4.9 | 7.9 | 73.2 | 52 | 24 | 23 | 9 | 40 | 64 | 0 | 3 | 2 | 0 | 0 | 2 | 2 | 4.58 |
| RP | Chavez, J.Chavez, Jesse >> | 38 | 2021 | R | 92 | 76 | 0 | 3 | 1 | 2.81 | .304 | 1.25 | 5.6 | 5.6 | 9.8 | 77.0 | 48 | 26 | 24 | 6 | 48 | 84 | 0 | 0 | 2 | 0 | 0 | 5 | 9 | 3.90 |
| RP | Rodriguez, R.Rodriguez, Richard >> | 31 | 2021 | R | 82 | 40 | 0 | 5 | 1 | 3.51 | .332 | 1.39 | 10.5 | 2.0 | 9.0 | 41.0 | 48 | 24 | 16 | 2 | 9 | 41 | 0 | 0 | 0 | 0 | 0 | 4 | 1 | 2.59 |
| RP | Williams, D.Williams, Devin >> | 26 | 2021 | R | 84 | 30 | 0 | 2 | 1 | 1.29 | .245 | 0.97 | 5.1 | 3.6 | 12.3 | 35.0 | 20 | 9 | 5 | 2 | 14 | 48 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2.20 |
| CL | Hendriks, L.Hendriks, Liam >> | 32 | 2021 | R | 100 | 63 | 0 | 9 | 4 | 2.12 | .277 | 1.08 | 7.7 | 2.1 | 10.1 | 63.2 | 54 | 17 | 15 | 6 | 15 | 71 | 0 | 35 | 4 | 0 | 0 | 4 | 3 | 2.89 |
| SU | Jansen, K.Jansen, Kenley >> | 33 | 2021 | R | 96 | 46 | 0 | 1 | 1 | 1.11 | .255 | 1.03 | 4.9 | 4.5 | 9.2 | 48.2 | 26 | 6 | 6 | 2 | 24 | 49 | 0 | 9 | 1 | 0 | 0 | 0 | 1 | 3.00 |