| SP | Morton, C.Morton, Charlie >> | 38 | 2021 | R | 95 | 35 | 35 | 16 | 10 | 3.92 | .302 | 1.25 | 7.8 | 3.4 | 10.1 | 208.2 | 181 | 93 | 91 | 25 | 79 | 233 | 0 | 0 | 0 | 0 | 16 | 11 | 13 | 3.62 |
| SP | Kershaw, C.Kershaw, Clayton >> | 33 | 2021 | L | 91 | 32 | 32 | 15 | 9 | 3.67 | .313 | 1.32 | 9.0 | 2.9 | 10.5 | 186.1 | 186 | 76 | 76 | 25 | 60 | 217 | 0 | 0 | 0 | 0 | 14 | 9 | 6 | 3.53 |
| SP | DeSclafani, A.DeSclafani, Anthony >> | 31 | 2021 | R | 80 | 11 | 11 | 6 | 3 | 5.11 | .335 | 1.44 | 10.0 | 3.1 | 7.7 | 56.1 | 62 | 33 | 32 | 11 | 19 | 48 | 0 | 0 | 0 | 0 | 5 | 4 | 3 | 5.07 |
| SP | Berrios, J.Berrios, Jose >> | 27 | 2021 | R | 87 | 33 | 33 | 14 | 5 | 4.41 | .351 | 1.58 | 10.3 | 3.9 | 9.4 | 191.2 | 219 | 96 | 94 | 24 | 83 | 199 | 0 | 0 | 0 | 0 | 17 | 9 | 2 | 3.99 |
| SU | Boxberger, B.Boxberger, Brad >> | 33 | 2021 | R | 90 | 79 | 0 | 5 | 3 | 2.38 | .284 | 1.14 | 6.7 | 3.6 | 11.4 | 90.2 | 67 | 24 | 24 | 4 | 36 | 114 | 0 | 3 | 2 | 0 | 0 | 5 | 3 | 2.41 |
| RP | Kennedy, I.Kennedy, Ian >> | 37 | 2021 | R | 75 | 42 | 0 | 4 | 3 | 4.30 | .346 | 1.57 | 9.0 | 5.1 | 9.0 | 46.0 | 46 | 26 | 22 | 5 | 26 | 46 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 4.17 |
| RP | McHugh, C.McHugh, Collin >> | 34 | 2021 | R | 92 | 58 | 0 | 5 | 3 | 3.39 | .286 | 1.15 | 6.8 | 3.6 | 10.4 | 85.0 | 64 | 33 | 32 | 7 | 34 | 98 | 0 | 0 | 0 | 0 | 0 | 4 | 5 | 3.11 |