| SP | Marquis, J.Marquis, Jason >> | 29 | 2004 | R | 22 | 26 | 25 | 9 | 7 | 5.06 | .343 | 1.52 | 9.7 | 4.0 | 6.1 | 126.1 | 136 | 73 | 71 | 22 | 56 | 86 | 0 | 1 | 0 | 0 | 7 | 6 | 1 | 5.38 |
| SP | Bannister, B.Bannister, Brian >> | 22 | 2007 | R | 60 | 8 | 8 | 3 | 3 | 5.04 | .321 | 1.38 | 10.1 | 2.3 | 4.3 | 50.0 | 56 | 30 | 28 | 9 | 13 | 24 | 0 | 0 | 0 | 0 | 4 | 2 | 2 | 5.28 |
| SP | Carmona, F.Carmona, Fausto # >> | 23 | 2007 | R | 72 | 26 | 24 | 10 | 8 | 5.39 | .319 | 1.39 | 9.7 | 2.9 | 6.6 | 135.1 | 145 | 88 | 81 | 28 | 43 | 99 | 0 | 0 | 0 | 0 | 5 | 2 | 3 | 5.23 |
| CL | Papelbon, J.Papelbon, Jonathan † >> | 25 | 2006 | R | 100 | 60 | 0 | 3 | 3 | 3.28 | .259 | 1.00 | 6.5 | 2.6 | 8.7 | 90.2 | 65 | 34 | 33 | 13 | 26 | 87 | 0 | 28 | 4 | 0 | 0 | 4 | 4 | 3.94 |
| SU | Zumaya, J.Zumaya, Joel >> | 25 | 2006 | R | 94 | 68 | 0 | 8 | 1 | 2.50 | .229 | 0.86 | 5.2 | 2.6 | 11.1 | 101.0 | 58 | 33 | 28 | 10 | 29 | 125 | 0 | 2 | 1 | 0 | 0 | 3 | 5 | 2.76 |
| RP | Turnbow, D.Turnbow, Derrick >> | 27 | 2005 | R | 84 | 83 | 0 | 8 | 6 | 4.47 | .278 | 1.13 | 7.4 | 2.8 | 9.0 | 116.2 | 96 | 59 | 58 | 15 | 36 | 116 | 0 | 4 | 4 | 0 | 0 | 3 | 9 | 3.69 |
| RP | Cordero, F.Cordero, Francisco >> | 30 | 2003 | R | 16 | 39 | 0 | 1 | 0 | 3.51 | .328 | 1.44 | 9.0 | 4.0 | 10.3 | 41.0 | 41 | 16 | 16 | 8 | 18 | 47 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 4.63 |