| SP | Richard, J.Richard, J.R. † >> | 30 | 1980 | R | 93 | 34 | 34 | 19 | 7 | 2.95 | .287 | 1.18 | 6.6 | 4.0 | 7.6 | 238.0 | 174 | 79 | 78 | 18 | 106 | 202 | 3 | 0 | 0 | 1 | 27 | 8 | 1 | 3.72 |
| SP | Harden, R.Harden, Rich >> | 27 | 2008 | R | 68 | 32 | 32 | 17 | 7 | 2.74 | .275 | 1.10 | 6.5 | 3.4 | 9.0 | 197.1 | 143 | 60 | 60 | 12 | 75 | 196 | 0 | 0 | 0 | 0 | 21 | 7 | 3 | 3.05 |
| SP | Fernandez, J.Fernandez, Jose # >> | 21 | 2013 | R | 83 | 32 | 32 | 14 | 12 | 3.33 | .291 | 1.20 | 7.5 | 3.3 | 9.0 | 194.2 | 161 | 78 | 72 | 17 | 72 | 194 | 0 | 0 | 0 | 0 | 20 | 7 | 1 | 3.36 |
| SP | Lincecum, T.Lincecum, Tim >> | 25 | 2009 | R | 59 | 31 | 31 | 13 | 10 | 4.05 | .305 | 1.29 | 8.5 | 3.1 | 9.6 | 195.2 | 184 | 92 | 88 | 27 | 68 | 207 | 6 | 0 | 0 | 2 | 20 | 6 | 7 | 3.82 |
| RP | Chapman, A.Chapman, Aroldis >> | 24 | 2012 | L | 88 | 85 | 0 | 5 | 6 | 3.09 | .269 | 1.08 | 5.7 | 3.9 | 9.3 | 105.0 | 67 | 37 | 36 | 15 | 46 | 108 | 0 | 17 | 4 | 0 | 0 | 3 | 3 | 4.20 |
| RP | Hader, J.Hader, Josh † >> | 24 | 2018 | L | 92 | 68 | 0 | 6 | 0 | 1.77 | .243 | 0.95 | 4.8 | 3.8 | 10.9 | 91.1 | 49 | 18 | 18 | 4 | 38 | 110 | 0 | 15 | 3 | 0 | 0 | 1 | 0 | 2.44 |
| RP | Eckersley, D.Eckersley, Dennis >> | 36 | 1990 | R | 86 | 42 | 0 | 2 | 2 | 2.76 | .279 | 1.14 | 8.4 | 1.8 | 8.3 | 49.0 | 46 | 15 | 15 | 6 | 10 | 45 | 0 | 8 | 3 | 0 | 0 | 1 | 0 | 3.43 |
| RP | Williams, D.Williams, Devin >> | 28 | 2023 | R | 70 | 29 | 0 | 4 | 6 | 2.87 | .271 | 1.12 | 4.9 | 5.2 | 9.0 | 31.1 | 17 | 10 | 10 | 4 | 18 | 31 | 0 | 4 | 3 | 0 | 0 | 0 | 0 | 4.42 |
| RP | Holland, G.Holland, Greg >> | 27 | 2013 | R | 70 | 22 | 0 | 2 | 1 | 1.64 | .250 | 1.00 | 6.1 | 2.9 | 11.0 | 22.0 | 15 | 4 | 4 | 2 | 7 | 27 | 0 | 5 | 0 | 0 | 0 | 0 | 1 | 2.68 |
| RP | Saucier, K.Saucier, Kevin >> | 25 | 1981 | L | 55 | 19 | 0 | 1 | 1 | 2.31 | .213 | 0.73 | 3.1 | 3.5 | 8.2 | 23.1 | 8 | 6 | 6 | 1 | 9 | 21 | 0 | 3 | 0 | 0 | 0 | 2 | 0 | 3.17 |
| SP | Rogers, S.Rogers, Steve >> | 24 | 1973 | R | 50 | 19 | 0 | 2 | 2 | 4.03 | .316 | 1.35 | 8.1 | 4.2 | 4.4 | 91.2 | 82 | 42 | 41 | 8 | 42 | 44 | 0 | 0 | 1 | 0 | 0 | 3 | 1 | 4.66 |