| SP | Gausman, K.Gausman, Kevin # >> | 34 | 2025 | R | 84 | 34 | 34 | 17 | 10 | 3.53 | .286 | 1.18 | 8.1 | 2.5 | 9.7 | 209.0 | 189 | 85 | 82 | 35 | 58 | 225 | 0 | 0 | 0 | 0 | 20 | 4 | 3 | 3.91 |
| SP | Skubal, T.Skubal, Tarik >> | 28 | 2025 | L | 100 | 36 | 36 | 14 | 11 | 3.61 | .276 | 1.10 | 7.8 | 2.1 | 10.6 | 264.0 | 228 | 107 | 106 | 32 | 63 | 311 | 5 | 0 | 0 | 2 | 21 | 11 | 0 | 3.06 |
| SP | Cameron, N.Cameron, Noah >> | 25 | 2025 | L | 80 | 34 | 34 | 10 | 12 | 3.83 | .305 | 1.25 | 8.2 | 3.1 | 7.9 | 209.1 | 190 | 94 | 89 | 35 | 71 | 184 | 0 | 0 | 0 | 0 | 17 | 14 | 7 | 4.64 |
| SP | Cabrera, E.Cabrera, Edward # >> | 27 | 2025 | R | 69 | 33 | 33 | 7 | 8 | 5.06 | .333 | 1.49 | 9.5 | 3.9 | 8.2 | 144.0 | 152 | 85 | 81 | 26 | 62 | 131 | 0 | 0 | 0 | 0 | 1 | 2 | 7 | 4.86 |
| CL | Santana, D.Santana, Dennis >> | 29 | 2025 | R | 92 | 93 | 0 | 2 | 12 | 3.40 | .285 | 1.18 | 7.5 | 3.1 | 8.6 | 92.2 | 77 | 35 | 35 | 10 | 32 | 88 | 0 | 43 | 5 | 0 | 0 | 2 | 0 | 3.61 |
| RP | Mattson, I.Mattson, Isaac >> | 29 | 2025 | R | 62 | 81 | 0 | 8 | 2 | 3.15 | .278 | 1.13 | 6.5 | 3.7 | 8.9 | 97.0 | 70 | 38 | 34 | 12 | 40 | 96 | 0 | 2 | 2 | 0 | 0 | 2 | 0 | 3.93 |
| RP | Rodríguez, Y.Rodríguez, Yariel >> | 28 | 2025 | R | 65 | 97 | 0 | 11 | 1 | 3.69 | .285 | 1.17 | 6.4 | 4.1 | 7.5 | 127.0 | 91 | 52 | 52 | 19 | 58 | 106 | 0 | 1 | 6 | 0 | 0 | 3 | 2 | 4.72 |
| RP | Coulombe, D.Coulombe, Daniel >> | 35 | 2025 | L | 61 | 68 | 0 | 5 | 4 | 3.82 | .300 | 1.25 | 8.2 | 3.1 | 11.3 | 75.1 | 68 | 34 | 32 | 12 | 26 | 94 | 0 | 1 | 0 | 0 | 0 | 3 | 3 | 3.73 |