| SP | Brown, B.Brown, Ben CHC >> | 24 | 2024 | R | 92 | 34 | 34 | 2 | 8 | 3.66 | .293 | 1.23 | 7.9 | 3.2 | 9.3 | 137.2 | 120 | 64 | 56 | 10 | 49 | 142 | 0 | 0 | 0 | 0 | 1 | 2 | 6 | 2.99 |
| SP | Waddell, R.Waddell, Rube CHC >> | 28 | 1904 | L | 91 | 33 | 33 | 18 | 11 | 2.98 | .302 | 1.28 | 8.9 | 2.7 | 6.0 | 259.2 | 255 | 97 | 86 | 18 | 77 | 172 | 15 | 0 | 0 | 5 | 20 | 5 | 3 | 3.53 |
| SP | Darvish, Y.Darvish, Yu CHC # >> | 33 | 2020 | R | 98 | 33 | 33 | 13 | 11 | 4.13 | .315 | 1.36 | 9.0 | 3.2 | 8.8 | 211.1 | 211 | 106 | 97 | 15 | 76 | 206 | 2 | 0 | 0 | 2 | 17 | 4 | 2 | 3.11 |
| SP | Imanaga, S.Imanaga, Shota CHC >> | 31 | 2025 | L | 93 | 32 | 32 | 13 | 8 | 4.30 | .329 | 1.46 | 10.0 | 3.1 | 5.2 | 182.0 | 203 | 96 | 87 | 16 | 63 | 106 | 0 | 0 | 0 | 0 | 12 | 2 | 7 | 4.05 |
| SP | Maddux, G.Maddux, Greg CHC # >> | 25 | 1991 | R | 76 | 31 | 31 | 14 | 9 | 4.79 | .319 | 1.40 | 9.5 | 3.1 | 5.6 | 188.0 | 199 | 105 | 100 | 17 | 65 | 116 | 1 | 0 | 0 | 1 | 18 | 0 | 4 | 3.98 |
| RP | Marmol, C.Marmol, Carlos CHC >> | 26 | 2008 | R | 97 | 73 | 0 | 6 | 1 | 2.34 | .305 | 1.30 | 5.7 | 6.0 | 9.5 | 96.1 | 61 | 30 | 25 | 5 | 64 | 101 | 0 | 9 | 4 | 0 | 0 | 2 | 5 | 3.64 |
| RP | Pagan, E.Pagan, Emilio SEA >> | 34 | 2025 | R | 96 | 67 | 0 | 5 | 5 | 3.72 | .306 | 1.30 | 7.9 | 3.8 | 8.9 | 87.0 | 76 | 41 | 36 | 4 | 37 | 86 | 0 | 5 | 2 | 0 | 0 | 2 | 2 | 2.97 |
| RP | Chapman, A.Chapman, Aroldis CHC >> | 31 | 2019 | L | 84 | 60 | 0 | 5 | 4 | 3.44 | .302 | 1.30 | 6.5 | 5.2 | 8.6 | 73.1 | 53 | 32 | 28 | 5 | 42 | 70 | 0 | 5 | 4 | 0 | 0 | 0 | 3 | 3.70 |
| RP | Eckersley, D.Eckersley, Dennis CHC >> | 34 | 1988 | R | 90 | 48 | 0 | 4 | 4 | 4.03 | .300 | 1.29 | 8.3 | 3.4 | 5.8 | 51.1 | 47 | 24 | 23 | 5 | 19 | 33 | 0 | 11 | 1 | 0 | 0 | 0 | 0 | 4.10 |
| RP | Smith, L.Smith, Lee CHC # >> | 26 | 1983 | R | 81 | 23 | 0 | 3 | 2 | 5.54 | .333 | 1.50 | 9.7 | 3.8 | 4.8 | 26.0 | 28 | 16 | 16 | 3 | 11 | 14 | 0 | 3 | 2 | 0 | 0 | 0 | 0 | 4.69 |
| RP | Brewer, J.Brewer, Jim CHC >> | 28 | 1965 | L | 59 | 27 | 0 | 1 | 0 | 2.29 | .321 | 1.42 | 5.7 | 7.2 | 5.7 | 35.1 | 22 | 10 | 9 | 2 | 28 | 22 | 0 | 2 | 0 | 0 | 0 | 0 | 1 | 4.89 |
| SP | Hendricks, K.Hendricks, Kyle CHC >> | 24 | 2014 | R | 75 | 32 | 3 | 16 | 3 | 4.18 | .317 | 1.38 | 9.5 | 2.9 | 5.9 | 150.2 | 159 | 74 | 70 | 11 | 49 | 98 | 0 | 0 | 0 | 0 | 2 | 2 | 0 | 3.67 |