| SP | Gilbert, L.Gilbert, Logan SEA >> | 28 | 2025 | R | 95 | 36 | 36 | 18 | 8 | 2.73 | .256 | 1.02 | 6.6 | 2.6 | 10.3 | 210.2 | 153 | 65 | 64 | 12 | 61 | 241 | 0 | 0 | 0 | 0 | 18 | 4 | 12 | 2.38 |
| SP | Gonzales, M.Gonzales, Marco SEA >> | 28 | 2020 | L | 89 | 35 | 35 | 16 | 10 | 2.88 | .264 | 1.06 | 8.0 | 1.5 | 7.5 | 234.0 | 208 | 79 | 75 | 19 | 40 | 194 | 2 | 0 | 0 | 2 | 27 | 4 | 0 | 2.96 |
| SP | Kirby, G.Kirby, George SEA # >> | 27 | 2025 | R | 58 | 35 | 35 | 16 | 10 | 3.60 | .270 | 1.08 | 7.7 | 2.0 | 10.0 | 195.0 | 166 | 82 | 78 | 21 | 44 | 216 | 0 | 0 | 0 | 0 | 20 | 6 | 4 | 2.95 |
| SP | Castillo, L.Castillo, Luis SEA >> | 32 | 2025 | R | 61 | 31 | 31 | 7 | 10 | 4.19 | .306 | 1.28 | 9.3 | 2.3 | 6.3 | 169.2 | 174 | 84 | 79 | 26 | 44 | 119 | 0 | 0 | 0 | 0 | 17 | 6 | 0 | 4.48 |
| SP | Moore, M.Moore, Mike SEA >> | 26 | 1985 | R | 55 | 32 | 32 | 11 | 13 | 4.49 | .335 | 1.50 | 10.9 | 2.6 | 7.0 | 194.1 | 234 | 112 | 97 | 30 | 57 | 150 | 0 | 0 | 0 | 0 | 18 | 3 | 6 | 4.39 |
| RP | Munoz, A.Munoz, Andres SEA >> | 26 | 2025 | R | 90 | 109 | 0 | 3 | 2 | 1.71 | .246 | 0.96 | 5.5 | 3.1 | 10.0 | 95.0 | 58 | 20 | 18 | 5 | 33 | 106 | 0 | 1 | 1 | 0 | 0 | 2 | 6 | 2.56 |
| SU | Schooler, M.Schooler, Mike SEA >> | 29 | 1991 | R | 82 | 65 | 0 | 3 | 1 | 1.62 | .256 | 1.02 | 6.8 | 2.4 | 6.6 | 61.0 | 46 | 11 | 11 | 1 | 16 | 45 | 0 | 1 | 4 | 0 | 0 | 1 | 1 | 2.57 |
| CL | Jackson, M.Jackson, Mike SEA † >> | 30 | 1994 | R | 100 | 72 | 0 | 4 | 2 | 1.47 | .225 | 0.85 | 5.5 | 2.1 | 8.5 | 73.1 | 45 | 12 | 12 | 2 | 17 | 69 | 0 | 55 | 4 | 0 | 0 | 2 | 0 | 2.25 |
| RP | Sherrill, G.Sherrill, George SEA >> | 30 | 2007 | L | 94 | 101 | 0 | 4 | 3 | 3.19 | .286 | 1.19 | 6.7 | 4.1 | 10.6 | 73.1 | 54 | 28 | 26 | 6 | 33 | 86 | 0 | 0 | 3 | 0 | 0 | 1 | 4 | 3.11 |
| RP | Diaz, E.Diaz, Edwin SEA >> | 31 | 2025 | R | 99 | 82 | 0 | 5 | 6 | 2.84 | .254 | 0.98 | 6.7 | 2.2 | 11.2 | 69.2 | 51 | 25 | 22 | 6 | 17 | 86 | 0 | 0 | 0 | 0 | 0 | 3 | 4 | 2.51 |
| SP | Johnson, R.Johnson, Randy SEA >> | 43 | 2006 | L | 53 | 35 | 3 | 7 | 5 | 3.95 | .320 | 1.41 | 9.1 | 3.6 | 5.9 | 111.2 | 112 | 55 | 49 | 13 | 45 | 73 | 0 | 0 | 1 | 0 | 2 | 1 | 1 | 4.45 |
| RP | Speier, G.Speier, Gabe >> | 30 | 2025 | L | 96 | 77 | 0 | 4 | 4 | 1.40 | .234 | 0.89 | 5.8 | 2.2 | 10.3 | 77.1 | 50 | 13 | 12 | 4 | 19 | 88 | 0 | 0 | 0 | 0 | 0 | 2 | 1 | 2.21 |