| SP | Greinke, Z.Greinke, Zack >> | 32 | 2015 | R | 94 | 36 | 36 | 18 | 11 | 2.85 | .269 | 1.08 | 6.9 | 2.8 | 4.9 | 259.0 | 199 | 83 | 82 | 28 | 81 | 142 | 7 | 0 | 0 | 0 | 26 | 6 | 7 | 4.32 |
| SP | Alexander, P.Alexander, Pete † >> | 28 | 1915 | R | 88 | 34 | 34 | 18 | 8 | 2.93 | .267 | 1.07 | 7.2 | 2.4 | 5.0 | 252.0 | 202 | 84 | 82 | 17 | 67 | 141 | 11 | 0 | 0 | 2 | 25 | 6 | 7 | 3.63 |
| SP | Snell, B.Snell, Blake $$ >> | 25 | 2018 | L | 80 | 33 | 33 | 13 | 7 | 3.47 | .297 | 1.23 | 7.1 | 4.0 | 8.6 | 191.2 | 150 | 79 | 74 | 24 | 85 | 183 | 0 | 0 | 0 | 0 | 18 | 8 | 7 | 4.18 |
| SP | Ryan, N.Ryan, Nolan $$ >> | 44 | 1991 | R | 73 | 31 | 31 | 12 | 15 | 4.48 | .310 | 1.32 | 7.4 | 4.4 | 7.8 | 187.0 | 154 | 102 | 93 | 22 | 92 | 162 | 3 | 0 | 0 | 0 | 15 | 6 | 10 | 4.37 |
| RP | Uehara, K.Uehara, Koji >> | 38 | 2013 | R | 100 | 95 | 0 | 8 | 2 | 3.08 | .255 | 0.99 | 6.5 | 2.5 | 8.7 | 128.2 | 93 | 48 | 44 | 13 | 35 | 124 | 0 | 8 | 4 | 0 | 0 | 4 | 0 | 3.30 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 77 | 0 | 8 | 2 | 4.05 | .298 | 1.26 | 7.1 | 4.4 | 7.7 | 93.1 | 73 | 45 | 42 | 11 | 45 | 80 | 0 | 10 | 1 | 0 | 0 | 1 | 0 | 4.30 |
| RP | Soriano, R.Soriano, Rafael >> | 24 | 2003 | R | 84 | 57 | 0 | 4 | 4 | 3.81 | .312 | 1.31 | 8.2 | 3.7 | 7.4 | 75.2 | 68 | 32 | 32 | 8 | 31 | 62 | 0 | 7 | 6 | 0 | 0 | 4 | 0 | 4.13 |
| RP | Balfour, G.Balfour, Grant >> | 31 | 2008 | R | 75 | 38 | 0 | 1 | 5 | 6.28 | .325 | 1.42 | 7.5 | 5.2 | 8.4 | 43.0 | 36 | 30 | 30 | 6 | 25 | 40 | 0 | 7 | 2 | 0 | 0 | 1 | 0 | 4.77 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 75 | 26 | 0 | 4 | 1 | 3.18 | .331 | 1.48 | 8.4 | 5.1 | 6.8 | 28.1 | 26 | 10 | 10 | 4 | 16 | 21 | 0 | 2 | 1 | 0 | 0 | 0 | 0 | 5.07 |
| RP | Zimmerman, J.Zimmerman, Jeff >> | 27 | 1999 | R | 70 | 32 | 0 | 1 | 2 | 3.00 | .239 | 0.94 | 5.0 | 3.5 | 7.0 | 36.0 | 20 | 12 | 12 | 3 | 14 | 28 | 0 | 2 | 1 | 0 | 0 | 0 | 0 | 3.69 |