| SP | Johnson, W.Johnson, Walter † >> | 26 | 1913 | R | 95 | 21 | 21 | 10 | 5 | 2.98 | .279 | 1.14 | 7.7 | 2.5 | 4.8 | 148.0 | 127 | 52 | 49 | 6 | 41 | 79 | 6 | 0 | 0 | 1 | 15 | 4 | 1 | 3.37 |
| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 95 | 20 | 20 | 8 | 9 | 3.64 | .263 | 1.04 | 5.7 | 3.6 | 8.2 | 131.0 | 83 | 54 | 53 | 24 | 53 | 120 | 3 | 0 | 0 | 1 | 12 | 4 | 2 | 4.85 |
| SP | Snell, B.Snell, Blake $ >> | 25 | 2018 | L | 81 | 20 | 20 | 12 | 5 | 3.47 | .310 | 1.34 | 7.4 | 4.7 | 7.8 | 116.2 | 96 | 49 | 45 | 11 | 60 | 101 | 1 | 0 | 0 | 0 | 9 | 1 | 2 | 4.07 |
| SP | Kluber, C.Kluber, Corey † # >> | 31 | 2017 | R | 90 | 20 | 20 | 10 | 6 | 3.27 | .280 | 1.13 | 8.3 | 2.0 | 8.1 | 145.2 | 133 | 62 | 53 | 10 | 32 | 130 | 6 | 0 | 0 | 1 | 13 | 5 | 5 | 2.87 |
| RP | Uehara, K.Uehara, Koji >> | 38 | 2013 | R | 100 | 51 | 0 | 2 | 1 | 2.41 | .228 | 0.89 | 6.0 | 2.0 | 8.6 | 71.0 | 47 | 22 | 19 | 8 | 16 | 68 | 0 | 5 | 3 | 0 | 0 | 0 | 0 | 3.23 |
| RP | Miller, A.Miller, Andrew >> | 31 | 2016 | L | 92 | 49 | 0 | 3 | 3 | 3.18 | .237 | 0.91 | 6.7 | 1.6 | 11.2 | 62.1 | 46 | 23 | 22 | 8 | 11 | 77 | 0 | 7 | 2 | 0 | 0 | 1 | 0 | 2.77 |
| RP | Gossage, R.Gossage, Rich >> | 30 | 1981 | R | 89 | 32 | 0 | 3 | 1 | 1.62 | .257 | 1.04 | 5.4 | 4.0 | 8.5 | 50.0 | 30 | 9 | 9 | 4 | 22 | 47 | 0 | 2 | 2 | 0 | 0 | 0 | 1 | 3.48 |
| RP | Soriano, R.Soriano, Rafael >> | 24 | 2003 | R | 84 | 27 | 0 | 2 | 0 | 1.64 | .256 | 1.03 | 7.9 | 1.4 | 9.0 | 33.0 | 29 | 6 | 6 | 2 | 5 | 33 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | 2.24 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 75 | 17 | 0 | 1 | 3 | 6.91 | .386 | 1.81 | 12.9 | 3.9 | 10.9 | 14.1 | 20 | 11 | 11 | 1 | 6 | 17 | 0 | 1 | 1 | 0 | 0 | 1 | 3 | 3.00 |
| RP | Marmol, C.Marmol, Carlos >> | 26 | 2008 | R | 71 | 17 | 0 | 0 | 0 | 4.15 | .342 | 1.56 | 7.4 | 6.9 | 4.8 | 17.1 | 14 | 8 | 8 | 1 | 13 | 9 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 5.00 |