| SP | deGrom, J.deGrom, Jacob >> | 33 | 2021 | R | 100 | 33 | 33 | 12 | 15 | 3.83 | .315 | 1.35 | 8.6 | 3.6 | 8.9 | 192.2 | 184 | 89 | 82 | 24 | 77 | 190 | 1 | 0 | 0 | 0 | 22 | 5 | 0 | 3.93 |
| SP | Cole, G.Cole, Gerrit # >> | 28 | 2019 | R | 91 | 34 | 34 | 10 | 9 | 4.87 | .315 | 1.37 | 8.8 | 3.6 | 9.3 | 194.0 | 189 | 106 | 105 | 28 | 77 | 200 | 0 | 0 | 0 | 0 | 20 | 2 | 2 | 4.04 |
| SP | Fernandez, J.Fernandez, Jose >> | 21 | 2013 | R | 76 | 35 | 32 | 7 | 12 | 7.21 | .373 | 1.74 | 11.0 | 4.7 | 8.0 | 156.0 | 190 | 129 | 125 | 32 | 82 | 138 | 0 | 0 | 0 | 0 | 8 | 6 | 4 | 5.59 |
| SP | Bender, C.Bender, Chief >> | 26 | 1910 | R | 71 | 34 | 31 | 13 | 9 | 5.09 | .337 | 1.52 | 10.3 | 3.4 | 4.2 | 196.1 | 225 | 115 | 111 | 28 | 73 | 92 | 5 | 2 | 0 | 1 | 13 | 1 | 5 | 5.05 |
| CL | Gagne, E.Gagne, Eric † >> | 27 | 2003 | R | 98 | 93 | 0 | 9 | 7 | 3.18 | .287 | 1.16 | 6.0 | 4.5 | 11.4 | 110.1 | 73 | 40 | 39 | 11 | 55 | 139 | 0 | 33 | 10 | 0 | 0 | 5 | 2 | 3.41 |
| SU | Saito, T.Saito, Takashi >> | 37 | 2007 | R | 91 | 100 | 0 | 5 | 4 | 3.38 | .325 | 1.43 | 8.7 | 4.3 | 7.3 | 106.2 | 102 | 46 | 40 | 13 | 51 | 86 | 0 | 2 | 4 | 0 | 0 | 1 | 0 | 4.44 |
| RP | Gallegos, G.Gallegos, Giovanny # >> | 27 | 2019 | R | 82 | 87 | 0 | 3 | 7 | 5.40 | .324 | 1.42 | 8.8 | 4.0 | 7.7 | 96.2 | 94 | 63 | 58 | 13 | 43 | 82 | 0 | 1 | 3 | 0 | 0 | 2 | 3 | 4.46 |
| RP | Pagan, E.Pagan, Emilio >> | 28 | 2019 | R | 76 | 79 | 0 | 7 | 3 | 4.20 | .324 | 1.43 | 9.3 | 3.7 | 9.0 | 98.2 | 101 | 47 | 46 | 16 | 40 | 98 | 0 | 0 | 0 | 0 | 0 | 1 | 3 | 4.38 |