| SP | Verlander, J.Verlander, Justin >> | 36 | 2019 | R | 99 | 21 | 21 | 7 | 7 | 3.58 | .287 | 1.19 | 8.0 | 2.8 | 8.9 | 133.1 | 118 | 57 | 53 | 13 | 41 | 131 | 1 | 0 | 0 | 0 | 14 | 2 | 0 | 3.27 |
| SP | Cole, G.Cole, Gerrit # >> | 28 | 2019 | R | 92 | 20 | 20 | 8 | 4 | 3.37 | .276 | 1.14 | 8.4 | 1.9 | 10.0 | 125.2 | 116 | 48 | 47 | 12 | 27 | 139 | 2 | 0 | 0 | 1 | 14 | 1 | 2 | 2.70 |
| SP | Hunter, C.Hunter, Catfish >> | 26 | 1972 | R | 81 | 20 | 20 | 8 | 5 | 5.59 | .354 | 1.63 | 11.3 | 3.5 | 4.6 | 112.2 | 141 | 72 | 70 | 17 | 43 | 57 | 1 | 0 | 0 | 0 | 7 | 1 | 5 | 5.13 |
| SP | Hernandez, F.Hernandez, Felix >> | 28 | 2014 | R | 80 | 21 | 20 | 6 | 9 | 5.62 | .338 | 1.47 | 9.9 | 3.4 | 8.2 | 113.2 | 124 | 76 | 71 | 12 | 43 | 103 | 0 | 0 | 0 | 0 | 7 | 7 | 6 | 3.88 |
| CL | Gagne, E.Gagne, Eric † >> | 27 | 2003 | R | 98 | 67 | 0 | 3 | 4 | 4.02 | .317 | 1.38 | 8.6 | 3.9 | 7.7 | 71.2 | 68 | 36 | 32 | 5 | 31 | 61 | 0 | 27 | 5 | 0 | 0 | 1 | 2 | 3.55 |
| SU | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 60 | 0 | 1 | 3 | 5.16 | .354 | 1.62 | 9.1 | 5.4 | 9.0 | 68.0 | 69 | 43 | 39 | 8 | 41 | 68 | 0 | 2 | 2 | 0 | 0 | 2 | 0 | 4.43 |
| RP | Boxberger, B.Boxberger, Brad >> | 26 | 2014 | R | 83 | 64 | 0 | 3 | 1 | 3.00 | .267 | 1.08 | 6.5 | 3.1 | 8.5 | 66.0 | 48 | 26 | 22 | 9 | 23 | 62 | 0 | 3 | 4 | 0 | 0 | 1 | 0 | 3.98 |
| RP | Holland, G.Holland, Greg >> | 27 | 2013 | R | 72 | 40 | 0 | 7 | 2 | 3.81 | .313 | 1.37 | 7.2 | 5.3 | 12.1 | 49.2 | 39 | 22 | 21 | 4 | 29 | 66 | 0 | 0 | 1 | 0 | 0 | 0 | 2 | 3.14 |