| SP | Buehler, W.Buehler, Walker >> | 26 | 2021 | R | 100 | 28 | 28 | 11 | 12 | 3.77 | .298 | 1.27 | 8.6 | 2.8 | 7.1 | 188.2 | 180 | 95 | 79 | 9 | 59 | 149 | 0 | 0 | 0 | 0 | 16 | 1 | 2 | 2.99 |
| SP | Spahn, W.Spahn, Warren >> | 30 | 1951 | L | 66 | 27 | 27 | 9 | 12 | 6.59 | .374 | 1.75 | 12.3 | 3.4 | 4.6 | 157.0 | 215 | 122 | 115 | 20 | 60 | 80 | 4 | 0 | 0 | 1 | 7 | 6 | 4 | 4.90 |
| SP | Maddux, G.Maddux, Greg † >> | 30 | 1996 | R | 88 | 27 | 27 | 15 | 7 | 3.36 | .293 | 1.21 | 9.2 | 1.7 | 5.6 | 192.2 | 197 | 76 | 72 | 13 | 37 | 119 | 5 | 0 | 0 | 1 | 19 | 6 | 5 | 3.31 |
| SP | Tanana, F.Tanana, Frank # >> | 31 | 1984 | L | 60 | 27 | 27 | 13 | 9 | 4.54 | .300 | 1.26 | 9.2 | 2.2 | 5.1 | 176.1 | 180 | 100 | 89 | 17 | 43 | 99 | 3 | 0 | 0 | 2 | 13 | 4 | 3 | 3.93 |
| SP | Osborne, D.Osborne, Donovan >> | 27 | 1996 | L | 63 | 26 | 26 | 9 | 11 | 5.66 | .363 | 1.66 | 11.0 | 4.0 | 5.7 | 157.1 | 192 | 110 | 99 | 17 | 69 | 99 | 0 | 0 | 0 | 0 | 11 | 8 | 4 | 4.62 |
| RP | Radinsky, S.Radinsky, Scott >> | 29 | 1997 | L | 69 | 41 | 0 | 3 | 2 | 4.70 | .368 | 1.72 | 11.1 | 4.5 | 6.4 | 38.1 | 47 | 29 | 20 | 4 | 19 | 27 | 0 | 0 | 5 | 0 | 0 | 1 | 0 | 4.53 |
| RP | Eckersley, D.Eckersley, Dennis >> | 42 | 1996 | R | 59 | 25 | 0 | 0 | 1 | 3.86 | .319 | 1.36 | 11.2 | 1.4 | 5.0 | 25.2 | 31 | 16 | 11 | 3 | 4 | 14 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 4.04 |
| SU | De Fratus, J.De Fratus, Justin >> | 26 | 2014 | R | 87 | 43 | 0 | 0 | 2 | 2.91 | .245 | 0.93 | 6.8 | 1.6 | 3.5 | 46.1 | 35 | 17 | 15 | 1 | 8 | 18 | 0 | 6 | 4 | 0 | 0 | 2 | 0 | 3.15 |
| SP | Johnson, D.Johnson, Dave >> | 31 | 1990 | R | 30 | 15 | 0 | 2 | 2 | 5.64 | .328 | 1.47 | 10.4 | 3.0 | 4.2 | 60.2 | 69 | 38 | 38 | 6 | 20 | 28 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 4.37 |