| SP | Kershaw, C.Kershaw, Clayton † >> | 28 | 2016 | L | 99 | 38 | 38 | 19 | 15 | 1.82 | .223 | 0.85 | 6.4 | 1.3 | 6.7 | 312.0 | 221 | 66 | 63 | 24 | 44 | 231 | 19 | 0 | 0 | 4 | 0 | 4 | 2 | 2.98 |
| SP | Arrieta, J.Arrieta, Jake † >> | 30 | 2016 | R | 94 | 37 | 37 | 20 | 12 | 2.83 | .275 | 1.13 | 6.6 | 3.6 | 6.3 | 258.0 | 189 | 88 | 81 | 24 | 102 | 180 | 4 | 0 | 0 | 1 | 0 | 3 | 5 | 4.03 |
| SP | Maeda, K.Maeda, Kenta # >> | 28 | 2016 | R | 84 | 37 | 36 | 13 | 17 | 5.04 | .328 | 1.44 | 9.3 | 3.6 | 7.1 | 189.1 | 196 | 108 | 106 | 30 | 76 | 149 | 0 | 0 | 0 | 0 | 0 | 5 | 5 | 4.77 |
| RP | Edwards, C.Edwards, Carl >> | 24 | 2016 | R | 98 | 100 | 0 | 11 | 2 | 1.39 | .197 | 0.72 | 3.8 | 2.7 | 7.6 | 149.0 | 63 | 26 | 23 | 6 | 45 | 126 | 0 | 12 | 1 | 0 | 0 | 2 | 7 | 2.78 |
| RP | Dayton, G.Dayton, Grant >> | 28 | 2016 | L | 97 | 90 | 0 | 7 | 5 | 1.35 | .204 | 0.76 | 4.9 | 1.9 | 7.6 | 126.1 | 69 | 23 | 19 | 7 | 27 | 106 | 0 | 13 | 3 | 0 | 0 | 1 | 1 | 2.71 |
| RP | Blanton, J.Blanton, Joe >> | 36 | 2016 | R | 89 | 60 | 0 | 6 | 0 | 1.56 | .239 | 0.93 | 5.5 | 2.9 | 7.2 | 80.2 | 49 | 14 | 14 | 3 | 26 | 64 | 0 | 4 | 0 | 0 | 0 | 1 | 0 | 2.90 |
| SP | Stripling, R.Stripling, Ross >> | 26 | 2016 | R | 50 | 32 | 27 | 8 | 10 | 6.48 | .366 | 1.71 | 11.9 | 3.6 | 5.2 | 116.2 | 154 | 85 | 84 | 15 | 46 | 67 | 0 | 1 | 0 | 0 | 0 | 2 | 3 | 4.77 |