| SP | Johnson, W.Johnson, Walter $ >> | 26 | 1913 | R | 95 | 21 | 21 | 8 | 9 | 3.72 | .314 | 1.34 | 9.1 | 3.0 | 6.1 | 145.1 | 147 | 65 | 60 | 13 | 48 | 98 | 2 | 0 | 0 | 1 | 12 | 5 | 0 | 3.91 |
| SP | Krause, H.Krause, Harry >> | 21 | 1909 | L | 72 | 19 | 19 | 3 | 8 | 6.03 | .349 | 1.61 | 10.4 | 4.0 | 4.4 | 112.0 | 130 | 81 | 75 | 15 | 50 | 55 | 0 | 0 | 0 | 0 | 6 | 0 | 3 | 5.10 |
| SP | Darvish, Y.Darvish, Yu >> | 26 | 2013 | R | 46 | 19 | 19 | 8 | 6 | 4.26 | .320 | 1.38 | 8.2 | 4.3 | 8.9 | 126.2 | 115 | 66 | 60 | 15 | 60 | 124 | 1 | 0 | 0 | 0 | 11 | 4 | 8 | 4.10 |
| CL | Hader, J.Hader, Josh † >> | 24 | 2018 | L | 94 | 37 | 0 | 3 | 8 | 2.47 | .256 | 1.01 | 5.9 | 3.3 | 11.1 | 43.2 | 28 | 12 | 12 | 3 | 16 | 53 | 0 | 22 | 2 | 0 | 0 | 1 | 0 | 2.63 |
| SU | Saito, T.Saito, Takashi >> | 37 | 2007 | R | 92 | 28 | 0 | 0 | 3 | 6.07 | .360 | 1.65 | 9.6 | 5.6 | 6.5 | 29.2 | 31 | 20 | 20 | 3 | 18 | 21 | 0 | 3 | 5 | 0 | 0 | 1 | 0 | 4.86 |
| RP | Clippard, T.Clippard, Tyler # >> | 26 | 2011 | R | 80 | 45 | 0 | 3 | 5 | 5.01 | .292 | 1.24 | 7.9 | 3.4 | 8.5 | 55.2 | 48 | 32 | 31 | 10 | 21 | 52 | 0 | 1 | 4 | 0 | 0 | 0 | 0 | 4.62 |
| RP | Bailey, A.Bailey, Andrew >> | 25 | 2009 | R | 66 | 35 | 0 | 3 | 0 | 2.76 | .300 | 1.26 | 8.2 | 3.4 | 7.9 | 32.2 | 29 | 12 | 10 | 5 | 12 | 28 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 4.50 |
| RP | Messersmith, A.Messersmith, Andy >> | 23 | 1968 | R | 57 | 15 | 0 | 1 | 1 | 3.28 | .310 | 1.32 | 6.2 | 5.9 | 4.6 | 35.2 | 24 | 13 | 13 | 0 | 23 | 18 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 4.03 |
| RP | Wilhelm, H.Wilhelm, Hoyt >> | 43 | 1965 | R | 69 | 16 | 0 | 1 | 0 | 4.91 | .340 | 1.50 | 8.6 | 4.9 | 5.3 | 22.0 | 21 | 13 | 12 | 5 | 12 | 13 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 6.55 |
| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 95 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |