| SP | Verlander, J.Verlander, Justin $ >> | 36 | 2019 | R | 99 | 13 | 13 | 7 | 4 | 3.09 | .240 | 0.91 | 6.1 | 2.1 | 7.5 | 96.0 | 65 | 33 | 33 | 10 | 22 | 80 | 1 | 0 | 0 | 0 | 11 | 4 | 2 | 3.50 |
| SP | Kluber, C.Kluber, Corey >> | 31 | 2017 | R | 90 | 13 | 13 | 5 | 5 | 4.98 | .325 | 1.42 | 9.6 | 3.2 | 8.7 | 86.2 | 92 | 53 | 48 | 14 | 31 | 83 | 0 | 0 | 0 | 0 | 7 | 2 | 1 | 4.34 |
| SP | Johnson, R.Johnson, Randy >> | 41 | 2004 | L | 84 | 12 | 12 | 2 | 7 | 6.03 | .338 | 1.50 | 10.2 | 3.4 | 9.0 | 68.2 | 77 | 52 | 46 | 15 | 26 | 68 | 0 | 0 | 0 | 0 | 5 | 2 | 2 | 5.10 |
| CL | Kimbrel, C.Kimbrel, Craig >> | 24 | 2012 | R | 100 | 20 | 0 | 0 | 4 | 2.36 | .200 | 0.75 | 3.8 | 3.1 | 9.0 | 26.2 | 11 | 7 | 7 | 3 | 9 | 26 | 0 | 10 | 1 | 0 | 0 | 0 | 2 | 3.54 |
| SU | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 17 | 0 | 1 | 0 | 2.89 | .273 | 1.13 | 6.0 | 4.5 | 7.5 | 18.2 | 12 | 6 | 6 | 3 | 9 | 15 | 0 | 2 | 3 | 0 | 0 | 0 | 0 | 5.00 |
| RP | Gossage, R.Gossage, Rich >> | 30 | 1981 | R | 89 | 31 | 0 | 2 | 2 | 4.19 | .295 | 1.25 | 7.7 | 3.7 | 7.9 | 34.1 | 29 | 18 | 16 | 4 | 14 | 30 | 0 | 1 | 2 | 0 | 0 | 0 | 2 | 4.00 |
| RP | Devine, J.Devine, Joey >> | 25 | 2008 | R | 80 | 13 | 0 | 1 | 0 | 1.13 | .172 | 0.63 | 3.4 | 2.3 | 8.4 | 16.0 | 6 | 2 | 2 | 1 | 4 | 15 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 2.69 |
| RP | Hoffman, T.Hoffman, Trevor >> | 31 | 1998 | R | 75 | 10 | 0 | 1 | 1 | 3.60 | .268 | 1.00 | 4.5 | 4.5 | 9.0 | 10.0 | 5 | 4 | 4 | 2 | 5 | 10 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 5.40 |