| SP | Kershaw, C.Kershaw, Clayton # >> | 28 | 2016 | L | 99 | 21 | 21 | 5 | 11 | 4.61 | .296 | 1.24 | 9.4 | 1.8 | 8.8 | 146.1 | 152 | 89 | 75 | 16 | 29 | 142 | 3 | 0 | 0 | 0 | 8 | 4 | 6 | 3.16 |
| SP | Santana, J.Santana, Johan >> | 25 | 2004 | L | 85 | 18 | 18 | 4 | 12 | 5.74 | .346 | 1.58 | 10.6 | 3.7 | 9.2 | 106.2 | 125 | 78 | 68 | 20 | 44 | 108 | 1 | 0 | 0 | 0 | 10 | 0 | 4 | 4.66 |
| CL | Chapman, A.Chapman, Aroldis † >> | 37 | 2025 | L | 96 | 40 | 0 | 5 | 3 | 3.49 | .261 | 1.06 | 6.6 | 3.1 | 8.8 | 38.2 | 28 | 16 | 15 | 7 | 13 | 37 | 0 | 25 | 4 | 0 | 0 | 0 | 1 | 4.47 |
| SU | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 85 | 33 | 0 | 0 | 1 | 4.05 | .275 | 1.11 | 9.0 | 1.1 | 7.4 | 33.1 | 33 | 15 | 15 | 4 | 4 | 27 | 0 | 4 | 1 | 0 | 0 | 1 | 1 | 3.39 |
| RP | Gallegos, G.Gallegos, Giovanny >> | 27 | 2019 | R | 81 | 32 | 0 | 2 | 2 | 5.40 | .329 | 1.47 | 10.6 | 2.7 | 7.6 | 33.1 | 39 | 21 | 20 | 7 | 10 | 28 | 0 | 0 | 1 | 0 | 0 | 0 | 2 | 4.97 |
| RP | Dotel, O.Dotel, Octavio >> | 29 | 2002 | R | 68 | 17 | 0 | 0 | 0 | 5.12 | .341 | 1.55 | 9.5 | 4.7 | 7.6 | 19.1 | 20 | 11 | 11 | 3 | 10 | 16 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 4.95 |
| SP | Chesbro, J.Chesbro, Jack >> | 30 | 1904 | R | 65 | 11 | 2 | 2 | 1 | 3.77 | .325 | 1.37 | 8.8 | 3.6 | 4.8 | 43.0 | 42 | 21 | 18 | 8 | 17 | 23 | 1 | 0 | 0 | 0 | 2 | 3 | 1 | 5.74 |