| SP | deGrom, J.deGrom, Jacob # >> | 37 | 2025 | R | 98 | 23 | 23 | 6 | 12 | 4.70 | .306 | 1.29 | 9.5 | 2.1 | 9.8 | 132.0 | 139 | 69 | 69 | 23 | 31 | 143 | 0 | 0 | 0 | 0 | 12 | 5 | 3 | 3.92 |
| SP | Gausman, K.Gausman, Kevin >> | 34 | 2025 | R | 84 | 22 | 22 | 12 | 6 | 4.78 | .340 | 1.50 | 10.0 | 3.5 | 6.6 | 130.0 | 145 | 75 | 69 | 19 | 50 | 96 | 0 | 0 | 0 | 0 | 12 | 6 | 1 | 4.72 |
| SP | Kelly, M.Kelly, Merrill >> | 36 | 2025 | R | 74 | 21 | 21 | 8 | 7 | 4.61 | .321 | 1.37 | 8.9 | 3.5 | 7.9 | 125.0 | 123 | 65 | 64 | 18 | 48 | 110 | 0 | 0 | 0 | 0 | 10 | 6 | 0 | 4.41 |
| SP | Verlander, J.Verlander, Justin >> | 42 | 2025 | R | 22 | 20 | 20 | 4 | 8 | 6.16 | .352 | 1.60 | 11.7 | 2.7 | 7.8 | 102.1 | 133 | 70 | 70 | 20 | 31 | 88 | 0 | 0 | 0 | 0 | 3 | 3 | 0 | 4.82 |
| CL | Okert, S.Okert, Steven † >> | 33 | 2025 | L | 96 | 40 | 0 | 2 | 2 | 1.55 | .213 | 0.74 | 4.3 | 2.5 | 11.0 | 40.2 | 19 | 7 | 7 | 3 | 11 | 49 | 0 | 29 | 1 | 0 | 0 | 3 | 0 | 2.58 |
| SU | Fisher, B.Fisher, Braydon >> | 24 | 2025 | R | 89 | 46 | 0 | 3 | 3 | 4.26 | .345 | 1.56 | 10.4 | 3.7 | 9.0 | 44.1 | 51 | 21 | 21 | 8 | 18 | 44 | 0 | 0 | 4 | 0 | 0 | 1 | 0 | 4.66 |
| RP | Miller, S.Miller, Shelby >> | 34 | 2025 | R | 82 | 53 | 0 | 3 | 2 | 5.16 | .343 | 1.55 | 10.0 | 4.0 | 9.3 | 52.1 | 58 | 31 | 30 | 5 | 23 | 54 | 0 | 2 | 1 | 0 | 0 | 1 | 4 | 3.56 |
| RP | Phillips, T.Phillips, Tyler >> | 27 | 2025 | R | 56 | 40 | 0 | 2 | 3 | 2.76 | .279 | 1.14 | 6.8 | 3.6 | 8.2 | 45.2 | 34 | 18 | 14 | 5 | 18 | 41 | 0 | 2 | 1 | 0 | 0 | 1 | 1 | 3.89 |
| RP | Lynch, D.Lynch, Daniel >> | 28 | 2025 | L | 18 | 65 | 0 | 1 | 1 | 5.37 | .365 | 1.67 | 11.3 | 3.9 | 6.4 | 58.2 | 73 | 35 | 35 | 8 | 25 | 41 | 0 | 0 | 0 | 0 | 0 | 3 | 2 | 4.83 |
| SP | Holmes, C.Holmes, Clay >> | 32 | 2025 | R | 40 | 23 | 1 | 3 | 1 | 4.90 | .342 | 1.52 | 9.3 | 4.5 | 6.9 | 82.2 | 85 | 46 | 45 | 10 | 41 | 63 | 0 | 0 | 1 | 0 | 1 | 3 | 3 | 4.66 |