| SP | Skubal, T.Skubal, Tarik >> | 28 | 2025 | L | 100 | 16 | 16 | 4 | 8 | 5.42 | .335 | 1.46 | 10.2 | 3.0 | 10.7 | 91.1 | 103 | 57 | 55 | 13 | 30 | 108 | 0 | 0 | 0 | 0 | 8 | 5 | 0 | 3.64 |
| SP | Glasnow, T.Glasnow, Tyler >> | 31 | 2025 | R | 88 | 17 | 16 | 7 | 1 | 4.04 | .320 | 1.40 | 7.4 | 5.3 | 8.7 | 82.1 | 67 | 39 | 37 | 11 | 48 | 79 | 0 | 0 | 0 | 0 | 3 | 1 | 3 | 4.61 |
| SP | Imanaga, S.Imanaga, Shota >> | 31 | 2025 | L | 83 | 15 | 15 | 6 | 5 | 4.58 | .312 | 1.30 | 8.7 | 3.1 | 7.8 | 88.1 | 85 | 47 | 45 | 18 | 30 | 76 | 1 | 0 | 0 | 1 | 7 | 5 | 4 | 5.13 |
| SP | Rodriguez, E.Rodriguez, Eduardo >> | 32 | 2025 | L | 5 | 18 | 15 | 3 | 7 | 6.46 | .350 | 1.56 | 10.7 | 3.3 | 7.2 | 78.0 | 93 | 57 | 56 | 18 | 29 | 62 | 0 | 0 | 0 | 0 | 2 | 4 | 1 | 5.68 |
| RP | Cleavinger, G.Cleavinger, Garrett >> | 31 | 2025 | L | 94 | 58 | 0 | 8 | 4 | 3.58 | .287 | 1.18 | 7.1 | 3.6 | 10.8 | 65.1 | 51 | 26 | 26 | 7 | 26 | 78 | 0 | 2 | 2 | 0 | 0 | 2 | 2 | 3.29 |
| RP | Suarez, R.Suarez, Robert >> | 34 | 2025 | R | 91 | 57 | 0 | 2 | 3 | 3.28 | .276 | 1.11 | 6.9 | 3.2 | 9.0 | 57.2 | 44 | 21 | 21 | 8 | 20 | 57 | 0 | 1 | 2 | 0 | 0 | 2 | 0 | 3.98 |
| RP | Sousa, B.Sousa, Bennett >> | 30 | 2025 | L | 79 | 52 | 0 | 2 | 1 | 4.47 | .294 | 1.20 | 7.4 | 3.4 | 9.3 | 58.1 | 48 | 29 | 29 | 8 | 22 | 60 | 0 | 3 | 3 | 0 | 0 | 3 | 3 | 4.02 |
| RP | Bender, A.Bender, Anthony >> | 30 | 2025 | R | 76 | 48 | 0 | 3 | 2 | 3.38 | .306 | 1.30 | 7.6 | 4.3 | 8.5 | 50.2 | 42 | 20 | 19 | 3 | 24 | 47 | 0 | 3 | 2 | 0 | 0 | 1 | 2 | 3.40 |
| RP | Banks, T.Banks, Tanner >> | 33 | 2025 | L | 68 | 45 | 0 | 1 | 3 | 3.39 | .282 | 1.10 | 8.1 | 1.8 | 9.0 | 61.0 | 55 | 23 | 23 | 13 | 12 | 61 | 0 | 8 | 1 | 0 | 0 | 5 | 1 | 4.61 |