| SP | deGrom, J.deGrom, Jacob >> | 33 | 2021 | R | 100 | 2 | 2 | 1 | 1 | 1.98 | .226 | 0.88 | 6.2 | 2.1 | 8.3 | 13.2 | 9 | 3 | 3 | 0 | 3 | 12 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 1.85 |
| SP | Arrieta, J.Arrieta, Jake >> | 29 | 2015 | R | 93 | 2 | 2 | 1 | 1 | 1.23 | .290 | 1.23 | 7.1 | 4.5 | 10.3 | 14.2 | 11 | 8 | 2 | 0 | 7 | 16 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 2.21 |
| SP | Hernandez, F.Hernandez, Felix >> | 28 | 2014 | R | 79 | 2 | 2 | 0 | 2 | 12.71 | .452 | 2.47 | 18.0 | 4.9 | 6.5 | 11.1 | 22 | 16 | 16 | 2 | 6 | 8 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.55 |
| SP | Waddell, R.Waddell, Rube >> | 29 | 1905 | L | 67 | 1 | 1 | 0 | 0 | 4.26 | .387 | 1.89 | 13.5 | 4.5 | 9.0 | 6.1 | 9 | 4 | 3 | 2 | 3 | 6 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 6.83 |
| RP | Chapman, A.Chapman, Aroldis >> | 26 | 2014 | L | 93 | 3 | 0 | 0 | 1 | 2.45 | .267 | 1.09 | 6.0 | 6.0 | 9.0 | 3.2 | 2 | 1 | 1 | 0 | 2 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 3.00 |
| RP | Soriano, R.Soriano, Rafael >> | 24 | 2003 | R | 84 | 3 | 0 | 0 | 0 | 13.50 | .455 | 2.50 | 22.5 | 0.0 | 13.5 | 2.0 | 5 | 3 | 3 | 1 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 6.50 |
| CL | Britton, Z.Britton, Zach >> | 28 | 2016 | L | 78 | 1 | 0 | 0 | 0 | 0.00 | .000 | 0.00 | - | - | - | 0.1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| RP | Sutter, B.Sutter, Bruce >> | 24 | 1977 | R | 67 | 5 | 0 | 0 | 0 | 3.86 | .300 | 1.29 | 13.5 | 0.0 | 6.8 | 4.2 | 6 | 4 | 2 | 1 | 0 | 3 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 4.75 |
| RP | Harvey, B.Harvey, Bryan >> | 28 | 1991 | R | 66 | 5 | 0 | 0 | 0 | 11.12 | .452 | 2.47 | 21.6 | 3.6 | 7.2 | 5.2 | 12 | 7 | 7 | 0 | 2 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 2.60 |
| SP | Darvish, Y.Darvish, Yu >> | 26 | 2013 | R | 46 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |